Odor Blockers for Smoking
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to explore whether blocking certain smells in cigarette smoke can help people stop smoking. Researchers seek to determine if reducing the smell of smoke decreases the urge to light up. Participants will smell various samples, including clean air, odorants (substances used to block or alter smells), and smoke, and report how each affects their desire to smoke. The study seeks smokers with a normal sense of smell and taste. As an unphased trial, participants have the unique opportunity to contribute to innovative research that could lead to new smoking cessation methods.
Do I need to stop my current medications to join the trial?
The trial information does not specify whether you need to stop taking your current medications.
What prior data suggests that these odor blockers are safe for use in smoking cessation?
Research shows that the odor blockers used in this trial are generally safe for people. Although specific proof of safety for this treatment is not yet available, the trial is in its early stages, and researchers are still collecting detailed safety information.
Similar studies with odorants have not reported major negative effects, indicating that participants have tolerated these substances well. Additionally, the treatments involve smelling odor samples, which is typically low-risk. While data on these specific odor blockers remains limited, the early stage of the trial ensures that researchers exercise caution as they gather more safety information.12345Why are researchers excited about this trial?
Researchers are excited about using odorants as a potential treatment for smoking because they offer a novel way to alter the smoking experience. Unlike traditional methods such as nicotine replacement therapies or prescription medications that target nicotine addiction directly, odorants work by modifying the sensory perception of cigarette smoke. By introducing blocking odors, this approach aims to make smoking less enjoyable, potentially reducing the urge to smoke. This sensory-based intervention could provide a complementary or alternative avenue for those struggling with smoking cessation.
What evidence suggests that odor blockers could be effective for smoking cessation?
Research has shown that certain smells can help reduce the urge to smoke. One study found that both pleasant and unpleasant smells decreased the desire to smoke compared to a neutral smell. In this trial, participants who smoke will encounter various odor samples, including blocking odors and cigarette smoke mixed with these odors. Smokers often have a weaker sense of smell, but quitting can enhance their ability to enjoy different scents. Using odor blockers might help people quit smoking by making cigarette smoke less appealing. Early evidence is promising, suggesting that smells could be a helpful tool in quitting smoking.36789
Who Is on the Research Team?
Timothy McClintock, PhD
Principal Investigator
University of Kentucky
Are You a Good Fit for This Trial?
This trial is for individuals who currently smoke cigarettes and can smell and taste normally. It's not suitable for non-smokers or those with a self-reported inability to smell or taste.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants are exposed to various odor samples, including controls, blocking odors, and cigarette smoke, and report on odor pleasantness and desire to smoke.
Follow-up
Participants are monitored for changes in smoking behavior and perception of odors after treatment sessions.
What Are the Treatments Tested in This Trial?
Interventions
- Odorants
Find a Clinic Near You
Who Is Running the Clinical Trial?
Tim McClintock
Lead Sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
Collaborator