Preventive Intervention for Tobacco-Related Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to understand how Ohio State University graduate students perceive the risks of oral nicotine pouches (ONPs) and how social influences impact their use. Researchers seek to develop effective communication strategies about the addictive risks of ONPs using social norms-based messages. Participants may complete an online survey or view visual risk messages about ONPs. This trial suits OSU graduate students who are 21 or older and have tried or are currently using ONPs, or feel at risk of starting. As an unphased trial, this study allows participants to contribute to important research on health communication and addiction prevention.
What prior data suggests that this preventive intervention is safe?
Research shows that programs designed to help people stop using tobacco can be safe and effective. These programs often use educational messages and social strategies to change perceptions of tobacco use. In this trial, participants will examine various visual messages about the risks of oral nicotine pouches (ONPs).
No evidence suggests that viewing these messages is unsafe for participants. Since this program focuses on changing perceptions through visual content, participants generally find it easy to handle. Other studies have safely used similar methods to help reduce health problems related to tobacco.
Overall, this program is considered safe for participants because it involves only viewing risk messages, without any physical or chemical treatments.12345Why are researchers excited about this trial?
Researchers are excited about this trial because it aims to discover how different types of messages can influence perceptions and behaviors related to tobacco use, specifically oral nicotine products (ONP). Traditional approaches often focus on quitting strategies or nicotine replacement therapies, but this trial is exploring how static and dynamic visual risk messages can impact user behavior. By understanding how these messages work, it could lead to innovative prevention strategies that are more effective in reducing tobacco-related cancer risks. This approach offers a fresh perspective by potentially shifting societal norms and personal perceptions through targeted communication.
What evidence suggests that this trial's preventive intervention could be effective for tobacco-related cancer?
Research shows that quitting smoking improves the chances of living longer. Studies have found that stopping smoking at any time enhances survival, with benefits noticeable at 3, 6, and 9 months after quitting. Combining methods like medication and counseling proves most effective in helping people quit smoking. For lung cancer, efforts to control tobacco use have significantly prevented deaths. This trial will explore interventions aimed at changing social norms and perceptions, such as those addressing oral nicotine pouch use, to effectively reduce tobacco-related risks. Participants will engage in different arms, including completing an online survey, viewing static or dynamic visual ONP risk messages, or viewing intervention messages in a randomized order.678910
Who Is on the Research Team?
Megan E Roberts, PhD
Principal Investigator
Ohio State University Comprehensive Cancer Center
Are You a Good Fit for This Trial?
This trial is for Ohio State University graduate students. It's focused on understanding how they think about health and behave socially, especially regarding oral nicotine pouches (ONPs). The goal is to learn if social pressures influence their use of ONPs.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Aim 1: Online Survey
Participants complete an online survey assessing ONP use patterns, perceptions of ONP-related norms, and interactions with ONP content on social media
Aim 2: Intervention Messages
Participants view four intervention messages in a randomized order and complete a questionnaire assessing perceived message effectiveness, ONP-related knowledge, risk perceptions, and self-efficacy
Aim 3: Message Exposure
Participants are randomly assigned to view either static or dynamic visual ONP risk messages and answer questions about their intentions to use ONPs, perceived susceptibility, beliefs, attitudes, and cognitive responses
Follow-up
Participants are monitored for changes in perceptions, attitudes, and behaviors related to ONP use
What Are the Treatments Tested in This Trial?
Interventions
- Preventive Intervention
Trial Overview
The study isn't testing a drug or medical treatment. Instead, it's looking at how effective certain communication strategies are in making students aware of the risks associated with using ONPs based on their perceptions and social behaviors.
How Is the Trial Designed?
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Treatment groups
Experimental Treatment
Active Control
Participants view dynamic visual ONP risk messages on study.
Participants view four intervention messages shown in a randomized order. These messages are randomly selected from five message blocks, which are part of a total pool of 33 messages.
Participants complete an online survey assessing ONP use patterns, perceptions of ONP-related norms, and interactions with ONP content on social media over 5-10 minutes on study.
Participants view static visual ONP risk messages on study.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Ohio State University Comprehensive Cancer Center
Lead Sponsor
National Cancer Institute (NCI)
Collaborator
Citations
Survival Outcomes of an Early Intervention Smoking ...
Smoking cessation treatment at 3 months, 6 months, or 9 months after initiation was associated with improved survival.
Survival Outcomes of an Early Intervention Smoking ...
Data also demonstrated that smoking cessation, regardless of time of entry, was associated with improved survival: abstinence at 3 months, 6 months, and 9 ...
3.
tobaccopreventioncessation.com
tobaccopreventioncessation.com/Effective-smoking-cessation-interventions-in-people-with-ncancer-A-systematic-review,211165,0,2.htmlEffective smoking cessation interventions in people with ...
Introduction: Continued smoking increases the risk of all-cause and cancer-specific mortality and adversely affects treatment outcomes.
The effectiveness of smoking cessation interventions after ...
Conclusion. A combination of pharmacological and behavioural interventions may be the most effective intervention for smoking cessation in patients with cancer.
5.
cancer.gov
cancer.gov/news-events/press-releases/2024/cancer-deaths-averted-prevention-screening-contributionImpacts of prevention, screening, treatment on cancer deaths
In lung cancer, prevention through tobacco control efforts accounted for 98% of the 3.45 million deaths averted (out of 9.2 million), and ...
Reducing Tobacco-Related Cancer Incidence and Mortality
Tobacco use is the leading cause of preventable death in the U.S.; approximately 30% of all cancer deaths and 80% of lung cancer deaths are due to tobacco use.
Disparities in Tobacco-Related Cancer Incidence and ...
Incidence of tobacco-related cancer decreased 1.3% per year, and mortality decreased 1.6% per year, with decreases observed across most ...
Evaluation of Population-Level Tobacco Control ...
In this systematic review and meta-analysis, smoke-free legislation was associated with significant reductions in morbidity and mortality related to CVD, RSD, ...
9.
tobaccopreventioncessation.com
tobaccopreventioncessation.com/pdf-211165-133474?filename=133474.pdfA systematic review and meta-analysis of randomized ...
This meta-analysis is of particular relevance because it was the first to evaluate the effectiveness of smoking cessation interventions in ...
Tobacco smoking and the risk of subsequent primary ...
Cancer survivors who recently stopped smoking had 18% less risk for developing all SPCs than current smokers. For smoking-related SPCs, ever and current smokers ...
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