250 Participants Needed

MOVED for PTSD

AP
Overseen ByAdam P McGuire, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: VA Office of Research and Development
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. However, it does mention that you cannot be actively participating in certain trauma-focused treatments.

What data supports the effectiveness of the treatment MOVED for PTSD?

The research on the Warrior Wellness study suggests that exercise, a component of MOVED, can improve PTSD symptoms in older veterans. Additionally, the MOVE! program, which is similar to MOVED, has shown effectiveness in weight management among veterans with PTSD, indicating potential benefits for overall health and well-being.12345

Is the MOVED treatment for PTSD safe for humans?

The available research does not provide specific safety data for the MOVED treatment for PTSD or any other conditions. However, studies emphasize the importance of assessing adverse events (unwanted effects) in mental health treatments, suggesting that safety monitoring is crucial in clinical trials.678910

What is the purpose of this trial?

Despite the availability of evidence-based treatments for PTSD, there are many challenges to successful trauma recovery for Veterans including difficulties starting and completing these treatments and gaps in fully addressing additional important treatment targets including lower social functioning and quality of life. Alternative, stand-alone treatment options that address a range of outcomes and can be easily accessed are needed to expand the reach of PTSD treatment to Veterans. One way to address this need is with a positive psychology intervention called MOVED, which has shown promise in a prior pilot study. MOVED is a web-based, self-guided intervention (8 sessions, 4 weeks) that uses moral elevation-feeling inspired by others' virtuous actions. This clinical trial will test if MOVED leads to decreased PTSD symptoms and increased social functioning and quality of life compared to a generic supportive treatment that does not focus on moral elevation. Results will help determine if MOVED is a useful alternative approach to target trauma recovery among Veterans with PTSD.

Research Team

AP

Adam P. McGuire, PhD

Principal Investigator

Central Texas Veterans Health Care System, Temple, TX

Eligibility Criteria

This trial is for veterans with PTSD who are looking for alternative treatment options. Participants should be open to web-based, self-guided sessions focusing on positive psychology. Specific eligibility criteria were not provided, so interested individuals should inquire further.

Inclusion Criteria

Enrolled in a VISN 17 health care system
Willingness to complete study procedures and be randomized
Internet access and an electronic device to complete the web-based sessions
See 2 more

Exclusion Criteria

Current psychosis or mania as indicated by medical record review and the Mini International Neuropsychiatric Interview (MINI)
Current suicide risk based on the Beck Depression Inventory-II (BDI-II)
I am currently in a trauma-focused therapy like CPT, PE, or EMDR.
See 1 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in a web-based, self-guided intervention (MOVED) or supportive care control for 8 sessions over 4 weeks

4 weeks
8 sessions (web-based)

Follow-up

Participants are monitored for PTSD symptoms, social functioning, and quality of life at posttreatment, 3-month, and 6-month follow-ups

6 months
3 follow-up assessments

Treatment Details

Interventions

  • MOVED
Trial Overview The MOVED program, a web-based intervention that promotes feelings of moral elevation through inspiring content over 8 sessions in 4 weeks, is being tested against a generic supportive care control to see if it can reduce PTSD symptoms and improve social functioning and quality of life.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: MOVEDExperimental Treatment1 Intervention
Moral Elevation Online Intervention for Veterans Experiencing Distress.
Group II: Supportive Care ControlActive Control1 Intervention
Present-centered, nondirective intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

VA Office of Research and Development

Lead Sponsor

Trials
1,691
Recruited
3,759,000+

Findings from Research

Women veterans and those who started evidence-based psychotherapy (EBP) within a year of seeking mental health care had higher chances of improving their PTSD symptoms, indicating the importance of timely intervention.
Completing at least 8 sessions of EBP and receiving specific therapies like Prolonged Exposure (PE) or Cognitive Processing Therapy (CPT) individually were linked to better outcomes, suggesting that both the timing and type of treatment can significantly influence recovery.
Factors associated with PTSD symptom improvement among Iraq and Afghanistan veterans receiving evidenced-based psychotherapy.Maguen, S., Holder, N., Li, Y., et al.[2021]
The study is evaluating the effectiveness of the Cancer Distress Coach mobile app versus usual care in 400 hematopoietic stem cell transplantation survivors experiencing PTSD symptoms, aiming to improve their quality of life.
Using a novel stepped-care SMART design, the trial will adapt treatment based on individual responses, potentially leading to more personalized and effective PTSD interventions for cancer survivors.
A SMART approach to optimizing delivery of an mHealth intervention among cancer survivors with posttraumatic stress symptoms.Smith, SK., Somers, TJ., Kuhn, E., et al.[2023]
The Warrior Wellness pilot study aims to assess the feasibility and effectiveness of a 12-week exercise program for older veterans (aged 60 and above) with PTSD, focusing on improving PTSD symptoms and cardiovascular endurance.
This study will provide insights into how regular exercise can impact the health of older veterans with PTSD, potentially leading to better treatment options and improved quality of life.
The Warrior Wellness Study: A Randomized Controlled Exercise Trial for Older Veterans with PTSD.Hall, KS., Morey, MC., Beckham, JC., et al.[2020]

References

Feasibility, acceptability and clinical benefit of a trauma-focused stabilisation group for post-traumatic stress disorder patients with complex presentations on primary care waitlists. [2023]
Factors associated with PTSD symptom improvement among Iraq and Afghanistan veterans receiving evidenced-based psychotherapy. [2021]
A SMART approach to optimizing delivery of an mHealth intervention among cancer survivors with posttraumatic stress symptoms. [2023]
The Warrior Wellness Study: A Randomized Controlled Exercise Trial for Older Veterans with PTSD. [2020]
Weight loss after participation in a national VA weight management program among veterans with or without PTSD. [2019]
Development of a Trigger Tool to Identify Adverse Events and Harm in a Neuropsychiatry Setting. [2023]
The Mental Health Trigger Tool: Development and Testing of a Specialized Trigger Tool for Mental Health Settings. [2023]
Exploring the experience of boarded psychiatric patients in adult emergency departments. [2021]
Defining and assessing adverse events and harmful effects in psychotherapy study protocols: A systematic review. [2023]
Adverse events in cognitive behavioral therapy and relaxation training for children and adolescents with obsessive-compulsive disorder: A mixed methods study and analysis plan for the TECTO trial. [2023]
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