Shockwave Therapy for Knee Arthritis
(PTOA Knee Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This study is recruiting current or former athletes who had ACL reconstruction surgery over a year ago and have been diagnosed with knee osteoarthritis (OA). We are doing the research to investigate the effects of extracorporeal shockwave therapy (ESWT) on pain, function, biomechanics, knee range of motion and strength, inflammation, and joint structure and integrity of the knee.
Are You a Good Fit for This Trial?
This trial is for current or former athletes who had ACL reconstruction surgery over a year ago and now have knee osteoarthritis. Participants should be diagnosed with post-traumatic knee OA to qualify.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants complete baseline assessments including biomechanical assessment, thermal imaging, bioimpedance, knee range of motion, quadriceps strength, and MRI of the knee.
Treatment
Participants receive ESWT or sham ESWT treatment over three sessions, with blood draws and biomarker analysis.
Follow-up
Participants are monitored for safety and effectiveness after treatment, with repeat assessments at 8 weeks and 4 months.
Optional Cross-over
Participants in the sham ESWT group have the option to cross-over and receive ESWT treatment.
What Are the Treatments Tested in This Trial?
Interventions
- Extracorporeal Shockwave Therapy
Extracorporeal Shockwave Therapy is already approved in United States for the following indications:
Find a Clinic Near You
Who Is Running the Clinical Trial?
Spaulding Rehabilitation Hospital
Lead Sponsor