Synthetic Nitrile vs Latex Condoms for STI Prevention
Trial Summary
Do I need to stop my current medications to join the trial?
The trial protocol does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of synthetic nitrile condoms compared to latex condoms for STI prevention?
Is it safe to use synthetic nitrile condoms for STI prevention?
How do synthetic nitrile condoms compare to latex condoms for STI prevention?
Synthetic nitrile condoms offer an alternative to latex condoms, potentially increasing user choice and encouraging more consistent condom use. They are made from synthetic materials, which may be more acceptable to some users, and have similar safety and efficacy in preventing sexually transmitted infections.134511
What is the purpose of this trial?
This trial tests new synthetic nitrile condoms against regular latex ones. Couples will use each type of condom and report their experiences. The goal is to see how well the new condoms work, how safe they are, and if people like them.
Research Team
Mags Beksinska, PhD
Principal Investigator
MatCH Research Unit (MRU)
Eligibility Criteria
Couples aged 18-45, in a monogamous relationship for at least 3 months, who are sexually active and agree to use only study condoms and lubricant. Excludes those with allergies to latex or nitrile, STI symptoms or HIV positive status, pregnant women or those wanting pregnancy soon, participants in other condom studies, employees of the trial's institutions, sex workers, men with sexual dysfunction and individuals with genital piercings.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants use five synthetic nitrile condoms (53 mm width), five synthetic nitrile condoms (56 mm width), and five latex male condoms in a randomised order, completing a Condom Use Report after each use.
Follow-up
Participants are monitored for functional performance, safety, and acceptability of the condoms used.
Treatment Details
Interventions
- Control Latex Condom
- Synthetic Nitrile Condoms (53mm)
- Synthetic Nitrile Condoms (56mm)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Karex Industries Sdn. Bhd.
Lead Sponsor
University of Witwatersrand, South Africa
Collaborator
Essential Access Health
Collaborator
Sigma3 Services SARL
Collaborator