Plant-Based Supplement for Body Fat
Trial Summary
What is the purpose of this trial?
The purpose of the current study is to examine the effects of a dietary supplement containing plant derived phenolics at two different dose levels in otherwise generally healthy adults with risk factors (high BMI at dyslipidemia and/or pre-diabetes) for body fat composition. The primary hypothesis is that supplementation with plant derived phenolics will decrease body fat composition compared to placebo.
Do I need to stop taking my current medications for the trial?
The trial does not require you to stop taking your current medications as long as they are stable, meaning the same dose for at least 90 days before the trial starts. You should maintain a stable intake of your current medications throughout the study.
What data supports the idea that Plant-Based Supplement for Body Fat is an effective treatment?
The available research shows that plant-based supplements containing polyphenols, like those from Hibiscus sabdariffa and Lippia citriodora, can help reduce body weight and abdominal circumference in overweight individuals. In one study, participants who took these supplements lost more inches around their waist compared to those who did not. Additionally, phenolic compounds found in plants have been shown to help manage obesity by reducing food intake and increasing the breakdown of fats. These findings suggest that plant-based supplements can be an effective treatment for reducing body fat.12345
What safety data exists for plant-based supplements for body fat reduction?
The safety data for plant-based supplements, specifically those containing polyphenols, is primarily derived from randomized controlled trials and reviews. These studies have evaluated the effects of polyphenolic extracts from plants like Hibiscus sabdariffa and Lippia citriodora in overweight and obese subjects. The trials were double-blind and placebo-controlled, indicating a rigorous approach to assessing safety and efficacy. While the focus is often on the efficacy of these supplements in reducing obesity-related parameters, the controlled nature of these studies suggests that safety is also monitored, although specific safety outcomes are not detailed in the abstracts provided.12345
Is the placebo treatment, Plant derived phenolics, a promising treatment for reducing body fat?
Yes, plant-derived phenolics, like those from Hibiscus and lemon verbena, have shown promise in reducing body fat and improving weight management. Studies have found that these natural compounds can help decrease body weight, reduce abdominal circumference, and lower fat mass, making them a promising treatment for managing obesity.12467
Eligibility Criteria
Adults over 18 with a BMI of 28-35, dyslipidemia (cholesterol issues), or pre-diabetes are eligible for this trial. They must have stable medication use for the past 90 days and not be current tobacco or nicotine users. Participants should maintain their current diet and supplement intake throughout the study.Inclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a dietary supplement containing plant-derived phenolics at two different dose levels or placebo
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Placebo treatment
- Plant derived phenolics
Find a Clinic Near You
Who Is Running the Clinical Trial?
Brightseed
Lead Sponsor