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Device

DBS Stimulation Patterns for Parkinson's Disease

N/A
Recruiting
Led By Aviva Abosch, MD, PhD
Research Sponsored by University of Nebraska
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patients optimized for clinical stimulation and medication for at least 3 months post-surgery for the implantation of their DBS system
Good response to stimulation (30% improvement on UPDRS III compared to baseline OFF), at least 3 months post-surgery
Timeline
Screening 3 weeks
Treatment Varies
Follow Up years 1-2
Awards & highlights

Study Summary

This trial is testing whether different stimulation patterns may be more efficient and effective in treating Parkinson's disease, with fewer side effects.

Who is the study for?
This trial is for Parkinson's Disease patients who have already had a specific brain stimulation device (Medtronic Percept PC) implanted and are responding well to treatment. They must consent to participate, have detectable brain signal patterns, be at least 3 months post-surgery, and optimized on their current therapy.Check my eligibility
What is being tested?
The study tests new stimulation patterns from the Medtronic Percept PC DBS device against standard ones in treating Parkinson's. It aims to see if these novel patterns can improve symptoms more effectively with fewer side effects.See study design
What are the potential side effects?
While not explicitly listed, potential side effects may include those typically associated with DBS adjustments such as speech problems, balance issues, tingling sensations or muscle contractions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I have been on medication and clinical stimulation for 3 months after my DBS system surgery.
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My condition improved by 30% after surgery, 3 months ago.
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I am recommended for deep brain stimulation for my Parkinson's Disease.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~years 1-2
This trial's timeline: 3 weeks for screening, Varies for treatment, and years 1-2 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Safety and Tolerability of novel DBS stimulation patterns.
Secondary outcome measures
Response to novel DBS stimulation patterns.

Trial Design

1Treatment groups
Experimental Treatment
Group I: PD with DBSExperimental Treatment1 Intervention
Patients with Parkinson's Disease who were implanted with Medtronic Percept PC for DBS and consent to participate in the study.

Find a Location

Who is running the clinical trial?

University of NebraskaLead Sponsor
535 Previous Clinical Trials
1,143,896 Total Patients Enrolled
Aviva Abosch, MD, PhD2.76 ReviewsPrincipal Investigator - University of Nebraska
University of Nebraska
3 Previous Clinical Trials
101 Total Patients Enrolled
5Patient Review
My lobectomy was handled with great care by Dr. Abosch and her team. I was in the hospital for 21 days, and they made sure to keep me and my husband informed and comfortable every step of the way. I'm still curious to know what they learn from my temporal lobe, but I'm grateful for the excellent care I received. We always recommend the University of Colorado to others looking for great doctors.

Media Library

Novel DBS stimulation patterns (Device) Clinical Trial Eligibility Overview. Trial Name: NCT04799470 — N/A
Parkinson's Disease Research Study Groups: PD with DBS
Parkinson's Disease Clinical Trial 2023: Novel DBS stimulation patterns Highlights & Side Effects. Trial Name: NCT04799470 — N/A
Novel DBS stimulation patterns (Device) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04799470 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there an age limitation for participants of this research initiative?

"This clinical trial seeks patients that are between 19 and 80 years of age."

Answered by AI

Are there any opportunities for me to be involved in this research project?

"As per the requirements for this medical study, patients must have parkinson's disease and be between 19 to 80 years old. Approximately 10 participants are required."

Answered by AI

How many participants has this trial been approved to enroll?

"Affirmative. Clinicaltrials.gov confirms that recruitment for this medical trial, which was initially posted on the 10th of May 2021, is ongoing. The research team seeks to enrol 10 patients from one clinical site."

Answered by AI

Is this research still enrolling participants?

"As documented on clinicaltrials.gov, this medical research is actively recruiting patients. The trial was first initiated on May 10th 2021 and recently modified on October 3rd 2022."

Answered by AI
~2 spots leftby Mar 2025