Neuromechanical Gait Assist for Paresis
Stimulation Combined With Powered Motorized Orthoses for Walking After Stroke
See full descriptionAbout the trial for Paresis
Treatment Groups
This trial involves 2 different treatments. Neuromechanical Gait Assist is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
Eligibility
This trial is for patients born any sex aged 18 and older. There are 9 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether Neuromechanical Gait Assist will improve 1 primary outcome and 12 secondary outcomes in patients with Paresis. Measurement will happen over the course of up to one year after baseline.
Patient Q & A Section
Can paresis be cured?
Paralysis of the upper limbs may be irreversible in some patients and its treatment may not be possible. In contrast, the lower limbs may be able to be reanimated by alternative means, which is why limb prosthesis should not be considered a definitive therapeutic response.
What are the signs of paresis?
Paresis involves weakness of the extremities, leading to slowness in movement and a weak or absent gait. The face often shows expressions of fear, and there may be decreased ability to speak.\n
What is paresis?
Paresis, also in the form of paraparesis or paraplegia, refers to partial or total paralysis of the limbs due to injury to the spinal cord. It results from a traumatic or medical condition.\n
How many people get paresis a year in the United States?
This is the first time that a specific disorder has been identified that is common to two or more different disability groups in the US. The findings suggest a high prevalence of paresis and the need for better evaluation and management of this condition in the US.
What causes paresis?
There are multiple possible causes for paresis. Doctors have tried different treatments to try to cure paresis, but nothing has made a long-term recovery. Many people with paresis find their balance impaired after surgery. Some people may find it more challenging to cope with their disability and may resort to the use of drugs for mood instability (including depression and anxiety), which worsen the problem. To help patients have a more peaceful living style, help them find a more comfortable paretics' chair at their residence and help them live their life comfortably. Most of the time doctors and patients try to understand each other and find a way to help each other to live their life to the optimal.
What are common treatments for paresis?
As there are no specific guidelines for the treatment of paresis, it is impossible to recommend a treatment approach that is optimal for every person. However, in principle, any of the medications mentioned may be prescribed. In practice, medications are more often prescribed first and then are supplemented with additional therapies such as behavioural or cognitive therapy. Corticosteroids are also sometimes prescribed, especially in neurologically severe cases. In children and adolescents, surgery to modify muscle spindles or to perform corrective exercises has traditionally been the modality of choice. In most cases, surgery is avoided and surgery is a last resort solution. Corticosteroids in combination with other medications are most commonly recommended in children because they appear to reduce side effects.
Does neuromechanical gait assist improve quality of life for those with paresis?
Those with spasticity or paresis have difficulty maintaining weight-bearing on hard surfaces due to a shorter step length. The use of the neuromechanical gait-assisted treadmill provides greater weight-bearing on hard surfaces than walking in an uncontrolled environment. Using the neuromechanical treadmill significantly improves the quality of life, particularly for those with paresis.
What is the average age someone gets paresis?
Paresis occurs at a rate of approximately 30% each decade after age 60. The majority of patients present with symptoms for many years before diagnosis. The younger patients tend to have acute symptoms; the older patients have more severe late symptoms.
Is neuromechanical gait assist typically used in combination with any other treatments?
The present study showed the efficacy of NMG in the management of patients with a functional deficit in the lower limbs, whose functional capacity or who were physically active at home and in everyday activities is affected. The combination of conventional treatments and NMG appears to be effective in improving gait gait speed.
Have there been any new discoveries for treating paresis?
Today we treat paresis with corticosteroids, stimulant drugs and anticonvulsants. But we had not seen any new discoveries for treating paresis until recent years. One new discovery is the administration of neurogenic hormones. Neurogenic hormones are hormones that regulate the normal functionality of the nervous system. This article describes the history of the administration of neurogenic hormones and the latest research findings. Neurogenic hormones may be a good candidate to treat paresis because they may help to regenerate axons and may help to relieve symptoms. Further clinical trials will be needed before neurogenic hormones are considered reliable therapy for paresis.
How does neuromechanical gait assist work?
PGA improves the ability of older adults with peripheral neuropathy to resist force while walking at the prescribed speed. PGA may therefore be a useful exercise for limiting muscle fatigue in older adults with neuropathic pain.
What does neuromechanical gait assist usually treat?
During walking or swing phase, ankle plantarflexor strength is not correlated with self-selected walking speed. Ankle plantarflexor strength is not the only measure that could assist recovery from ankle plantarflexor weakness; other functional measures must be explored in order to provide an understanding of the limitations of plantarflexing gait and to help determine how much neuromuscular training will assist recovery from paresis after stroke.