GO MOVE Home Program for Cerebral Palsy

Overseen By Heather Roberts, PhD

Age: < 18

Sex: Any

Trial Phase: Academic

Sponsor: Texas Scottish Rite Hospital for Children

Disqualifiers: Uncontrolled epilepsy, Visual impairment, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: 6 weeks

50 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests Go Move, a mobile website designed to help young people with unilateral cerebral palsy and their caregivers set and achieve physical activity goals. The study aims to determine if Go Move is helpful and accepted by these users. Participants will use the website to follow a home program for six weeks, spending a little over an hour each week on it. This trial suits young people aged 3-17 who have unilateral cerebral palsy and can access the Go Move website on their device. As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could enhance daily life for young people with cerebral palsy.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on using a mobile website for exercises, so it's unlikely that medication changes are required.

What prior data suggests that the Go Move program is safe for youth with cerebral palsy?

Research shows that the Go Move program, a mobile website for children with unilateral cerebral palsy, helps users set goals, choose activities, and track progress at home. Specific safety data for Go Move is unavailable because it is a digital tool, not a medicine or physical treatment. However, as a website, it is generally considered safe, similar to other online educational and planning tools. Feedback from participants in earlier studies improved the website's content and features, indicating that the program is user-friendly and well-received. Overall, Go Move is expected to be safe and easy for both children and their caregivers. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the Go Move Home Program for cerebral palsy because it offers a personalized, goal-driven approach that can be implemented at home. Unlike traditional therapies that often require frequent visits to specialized centers, this program empowers families to integrate therapeutic activities into their daily routines, potentially increasing the consistency and frequency of the exercises. This could lead to improved motor skills and flexibility in a more comfortable and familiar environment, making it easier for individuals with cerebral palsy to engage in their treatment.

What evidence suggests that the Go Move program is effective for cerebral palsy?

Research shows that the Go Move Home Program, a mobile website, helps kids with cerebral palsy set goals and choose activities at home. Studies indicate that programs like this can improve motor skills by focusing on specific goals. Evidence supports that this type of training enhances movement quality and increases satisfaction for both the child and their parents. Additionally, virtual reality (VR) has improved motor function in children with cerebral palsy. These findings suggest that using technology like Go Move, tested in this trial, may effectively support reaching goals and improving motor skills. ^{1 2 3 5 6}

Who Is on the Research Team?

Angela Shierk, PhD

Principal Investigator

Scottish Rite for Children

Are You a Good Fit for This Trial?

This trial is for children and teens aged 3-17 with unilateral cerebral palsy who can follow directions, use a personal device to access the Go Move website, and are not restricted by their doctor from daily activities. It's open to all ethnic/racial groups. Those with severe visual impairments, uncontrolled epilepsy, or behavioral issues cannot participate.

Inclusion Criteria

All ethnic/racial groups eligible to participate

I am between 3 and 17 years old.

I can walk without limitations or with some limitations.

Exclusion Criteria

I cannot follow the study's required assessments or home activities.

I have epilepsy that is not well-controlled.

I have major difficulty seeing.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2 weeks

Pre-intervention Assessment

Participants complete pre-intervention assessments including COPM, GAS Light, MACS, and demographic information

2 weeks

Treatment

Participants engage in a goal-driven home program using the Go Move mobile website for 6 weeks

6 weeks

Weekly home program participation

Post-intervention Assessment

Participants complete post-intervention assessments including COPM, GAS Light, and MARS

2 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Go Move

Trial Overview The study tests the acceptability and effectiveness of 'Go Move', a mobile site designed to help youth with unilateral cerebral palsy set goals and choose exercises. Participants will engage in a home program for over an hour weekly for six weeks while using Go Move.

How Is the Trial Designed?

Group I: Go Move Home Program Experimental Treatment 1 Intervention

Goal driven home program

Who Is Running the Clinical Trial?

Texas Scottish Rite Hospital for Children

Lead Sponsor

Trials

23

Recruited

9,000+

Published Research Related to This Trial

In a 3-month pilot study involving 3 adolescents with severe hemiplegic cerebral palsy, in-home virtual reality videogame telerehabilitation significantly improved hand function and finger range of motion, as assessed by standardized occupational therapy tests and remote measurements.

The two participants who adhered most closely to the rehabilitation regimen also showed improvements in forearm bone health, and all participants exhibited changes in brain motor circuitry activation during fMRI, indicating that the therapy not only enhanced physical function but also influenced brain activity related to movement.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

In-home virtual reality videogame telerehabilitation in adolescents with hemiplegic cerebral palsy. Golomb, MR., McDonald, BC., Warden, SJ., et al.[2022]

A study involving 34 children with cerebral palsy showed that individualized, supervised home-based training delivered via the internet significantly improved daily activities and upper and lower limb functions after 20 weeks of training.

The children in the training group completed an average of 17 minutes of daily exercises, leading to measurable functional improvements, while the control group showed no changes, highlighting the effectiveness of this training approach.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Twenty weeks of home-based interactive training of children with cerebral palsy improves functional abilities. Lorentzen, J., Greve, LZ., Kliim-Due, M., et al.[2018]

In a study involving 32 children with spastic hemiparetic cerebral palsy, a combination of modified constraint-induced movement therapy and virtual reality led to significant improvements in upper limb function, including limb use, movement quality, and speed and dexterity after 18 hours of training over 4 weeks.

These improvements were not only significant immediately after the treatment but were also maintained three months later, suggesting that this combined therapy could be an effective long-term rehabilitation strategy.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Effects of modified constraint-induced movement therapy in virtual environment on upper-limb function in children with spastic hemiparetic cerebral palsy: a randomised controlled trial. Rostami, HR., Arastoo, AA., Nejad, SJ., et al.[2012]

The iMOVE therapy, designed for young children with cerebral palsy (CP), aims to enhance motor learning and postural control by allowing children to self-initiate movement experiences, potentially leading to better outcomes than conventional therapy.

This study will involve 42 participants aged 1-3 years in a randomized controlled trial over 12-24 weeks, measuring gross motor function and other outcomes, which could provide valuable insights into early interventions for optimizing motor development in children with CP.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

iMOVE: Intensive Mobility training with Variability and Error compared to conventional rehabilitation for young children with cerebral palsy: the protocol for a single blind randomized controlled trial. Prosser, LA., Pierce, SR., Dillingham, TR., et al.[2023]

This trial will assess the combined efficacy and safety of virtual reality (VR) and repetitive transcranial magnetic stimulation (rTMS) in improving musculoskeletal pain and motor development in children aged 3-10 with unilateral spastic cerebral palsy, involving 2 treatment sessions over 4 weeks.

The study aims to determine if the combination of VR and rTMS provides better pain relief and motor function improvements compared to rTMS alone or a control group, with safety monitored throughout the trial.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Effect of virtual reality combined with repetitive transcranial magnetic stimulation on musculoskeletal pain and motor development in children with spastic cerebral palsy: a protocol for a randomized controlled clinical trial. Li, X., Huang, Z., Lu, T., et al.[2023]

A study involving 101 children with unilateral cerebral palsy showed that 20 weeks of web-based training significantly improved functional strength and walking endurance, with participants completing an average of 32.4 hours of training.

Despite the improvements in strength and endurance, the training did not lead to better overall activity performance, indicating that while the intervention was effective in certain areas, it may not enhance daily activities.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

A randomized controlled trial of web-based training to increase activity in children with cerebral palsy. Mitchell, LE., Ziviani, J., Boyd, RN.[2017]

A new virtual rehabilitation tool was tested on two adolescent patients with unilateral spastic cerebral palsy, showing significant improvements in upper-limb motor function as measured by the box and block test scores after 2 weeks of intervention.

The results indicated high effectiveness, with nonoverlap of all pairs indices of 0.95 and 0.93 for the paretic hand, suggesting that the virtual reality intervention can be a promising treatment option for enhancing motor skills in CP patients.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

A new virtual reality tool for unilateral cerebral palsy rehabilitation: two single-case studies. Dinomais, M., Veaux, F., Yamaguchi, T., et al.[2018]

The Tele-UPCAT program, which uses Action Observation Training (AOT) principles, was found to be feasible for home-based rehabilitation in 29 children and adolescents with Unilateral Cerebral Palsy (UCP), with 80% of training sessions completed successfully.

Participants reported high usability and acceptability scores for the Tele-UPCAT system, indicating that it is a promising approach for enhancing upper limb rehabilitation in UCP patients.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Feasibility of a Home-Based Action Observation Training for Children With Unilateral Cerebral Palsy: An Explorative Study. Beani, E., Menici, V., Ferrari, A., et al.[2020]

A pilot study involving 9 children with cerebral palsy demonstrated that individualized, supervised home-based training delivered via the internet can effectively maintain intensive training over 20 weeks, leading to significant improvements in motor strength and cognitive abilities.

Participants reported high satisfaction with the training, and on average, they engaged in over 74 hours of training, resulting in enhanced functional muscle strength and visual perceptual skills, indicating that this method can be a viable alternative to traditional therapy.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Individualized, home-based interactive training of cerebral palsy children delivered through the Internet. Bilde, PE., Kliim-Due, M., Rasmussen, B., et al.[2021]

In a study involving 42 children with cerebral palsy, both iMOVE therapy and conventional therapy showed similar effectiveness in improving gross motor function, with no significant differences in outcomes after 12 or 24 weeks of treatment.

Despite the lack of superiority, a significant number of participants (77%) exceeded expected improvements after 24 weeks, suggesting that both therapies may be more effective than standard care, and that iMOVE therapy encouraged more independent practice and child-initiated activities.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Motor training for young children with cerebral palsy: A single-blind randomized controlled trial. Prosser, LA., Pierce, SR., Skorup, JA., et al.[2023]

In a pilot study involving 11 children with cerebral palsy, the group that underwent a 1-week virtual reality (VR) intervention followed by a 6-week home active video gaming (AVG) program did not show significant improvements in gross motor skills compared to the AVG-only group.

The AVG-only group showed a significant improvement in gross motor function, while the VR + AVG group experienced a notable decrease in walking distance, indicating that the combination of VR and AVG may not be beneficial and could even be counterproductive.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Active Video Gaming for Children with Cerebral Palsy: Does a Clinic-Based Virtual Reality Component Offer an Additive Benefit? A Pilot Study. Levac, D., McCormick, A., Levin, MF., et al.[2018]

Virtual reality (VR) shows potential benefits for children with cerebral palsy (CP), with positive outcomes reported in areas like motor capacity and social participation across 12 out of 13 studies analyzed.

Despite some promising results, the overall quality of evidence is low, and more rigorous studies are needed to better understand the efficacy of VR as an intervention for CP.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Virtual reality as a therapeutic modality for children with cerebral palsy. Snider, L., Majnemer, A., Darsaklis, V.[2022]

The Interactive Virtual Reality Exercise (IREX) system was found to be a feasible rehabilitation tool for children with cerebral palsy, as assessed through an 8-week program involving five participants in a rural school setting.

Children reported the IREX intervention as fun and beneficial, highlighting that with proper supervision and therapist involvement, virtual rehabilitation can effectively support physiotherapy for those in isolated areas.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Virtual rehabilitation in a school setting: is it feasible for children with cerebral palsy? Rosie, JA., Ruhen, S., Hing, WA., et al.[2014]

Virtual reality training using the Xbox Kinect showed improvements in motor function, balance, gait, and functional mobility in four children with spastic diplegic cerebral palsy after 12 sessions over 4 weeks.

Each child demonstrated specific improvements in various physical function measures, indicating that VR training may be a beneficial intervention for enhancing physical abilities in children with CP, though more research is needed to confirm its effectiveness.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Does virtual reality training using the Xbox Kinect have a positive effect on physical functioning in children with spastic cerebral palsy? A case series. Jung, SH., Song, SH., Kim, SD., et al.[2019]

Citations

1. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov/38281146/

A Website for Children With Unilateral Cerebral Palsy GO Move, a mobile website aimed to provide information on goal setting, activity selection, and tracking of exercises and activities in the home environment.

2. withpower.com withpower.com/trial/phase-paralysis-8-2023-e646e

GO MOVE Home Program for Cerebral Palsy Research shows that using virtual reality (VR) as part of therapy can help improve motor skills in children with cerebral palsy. Studies have found that VR can ...

3. journals.sagepub.com journals.sagepub.com/doi/pdf/10.1177/15394492231225141?download=true

A Website for Children With Unilateral Cerebral Palsy GO Move, a mobile website aimed to provide information on goal setting, activity selection, and tracking of exercises and activities in the home environment for ...

4. twu-ir.tdl.org twu-ir.tdl.org/items/6dc74f61-3889-401e-a135-c34737f8534a

Go Move: A Case Study on Goal-Directed Training & Home ... Empirical evidence supports the efficacy of these approaches in enhancing function, parental contentment, and movement quality among youth with cerebral palsy ( ...

5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC6692882/

Effectiveness of Virtual Reality in Children With Cerebral Palsy Researchers recently investigated the effectiveness of virtual reality (VR) in helping children with cerebral palsy (CP) to improve motor function.

6. researchgate.net researchgate.net/publication/377765521_Development_of_GO_Move_A_Website_for_Children_With_Unilateral_Cerebral_Palsy

A Website for Children With Unilateral Cerebral Palsy Participants provided recommendations regarding content and features, and the GO Move mobile website was developed based on the recommendations.