Exercise for Stress-Related Eating

KT
Overseen ByKristina T Legget, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: VA Office of Research and Development
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Approved in 1 JurisdictionThis treatment is already approved in other countries

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how exercise might alter brain responses to thinking tasks and images of food. Researchers are also examining how hormones, which can differ between men and women, might affect these brain changes. Participants will either join an exercise program or continue their usual activities for 12 weeks. The study seeks veterans with a BMI of 25 or greater, who are physically inactive, and can attend sessions in Aurora, CO. As an unphased trial, this study provides a unique opportunity to contribute to understanding the impact of exercise on brain function.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the study team or your doctor.

What prior data suggests that exercise is safe for stress-related eating?

Research shows that exercise is generally safe and well-tolerated by most people. It effectively relieves stress and boosts mood by releasing feel-good chemicals in the brain. Studies consistently find that regular exercise helps manage stress and improves overall mental health.

However, excessive exercise can have negative effects, potentially causing injuries or becoming addictive, which may concern individuals with certain mental health conditions. These issues are uncommon with moderate exercise routines like the one in this trial, which gradually increases in intensity and duration.

In this study's exercise program, participants will begin with 15-minute sessions and gradually work up to 45 minutes. This gradual approach reduces the risk of injury and keeps the exercise safe and manageable. Always consult a healthcare provider before starting any new exercise program, especially if existing health concerns are present.12345

Why are researchers excited about this trial?

Researchers are excited about using exercise to tackle stress-related eating because it's a natural and accessible way to manage the condition. Unlike traditional approaches that might focus on dietary restrictions or medications to control eating habits, exercise offers a holistic benefit. It not only helps in managing stress but also boosts mood and energy levels, making it easier for individuals to cope with triggers that lead to overeating. Plus, incorporating regular exercise can improve overall health, providing a dual benefit of physical fitness and emotional well-being.

What evidence suggests that exercise might be an effective treatment for stress-related eating?

Research shows that exercise, which participants in this trial may engage in, can improve mood and self-esteem while reducing stress, often leading to stress-related eating. Studies have found that regular physical activity boosts self-confidence and helps control behaviors like stress eating. Exercise also protects against stress and negative feelings, leading to a better overall mood. These benefits make exercise a promising way to manage stress-related eating.678910

Who Is on the Research Team?

JR

Jason R. Tregellas, PhD

Principal Investigator

Rocky Mountain Regional VA Medical Center, Aurora, CO

KT

Kristina T. Legget, PhD

Principal Investigator

Rocky Mountain Regional VA Medical Center, Aurora, CO

Are You a Good Fit for This Trial?

This trial is for veterans struggling with obesity and stress-related eating behaviors. Participants should be able to perform physical activities as the study involves exercise interventions.

Inclusion Criteria

Physically inactive
BMI of 25 or greater
I can go to Aurora, CO for study visits.
See 1 more

Exclusion Criteria

Unable to pass screening graded exercise treadmill test
Currently pregnant
I cannot have an MRI due to weight, claustrophobia, or having metal/electronic implants.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Baseline Assessment

Participants complete initial assessments including serum cortisol response, BOLD response to visual food cues, heart rate response, body fat, and body weight measurements

1 week
1 visit (in-person)

Intervention

Participants either engage in 4 aerobic exercise sessions per week or continue usual activities for 12 weeks

12 weeks
12 visits (in-person, weekly)

Post-Intervention Assessment

Participants complete follow-up assessments including serum cortisol response, BOLD response to visual food cues, heart rate response, body fat, and body weight measurements

1 week
1 visit (in-person)

Follow-up

Participants are monitored for any long-term effects of the intervention

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Exercise
Trial Overview The study is examining how exercise affects brain responses during cognitive tasks and when viewing food images, considering hormonal differences between genders that may influence these effects.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: ExerciseExperimental Treatment1 Intervention
Group II: Usual activityActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

VA Office of Research and Development

Lead Sponsor

Trials
1,691
Recruited
3,759,000+

Published Research Related to This Trial

A scoping review of 10 studies and 6 reviews from 2021-2023 found that supervised and adapted physical activity (PAE) effectively managed dysfunctional exercise (DEx) in individuals with eating disorders, showing low-to-moderate health impacts and no adverse events.
For anorexia nervosa, PAE improved physical fitness without affecting body weight unless resistance training was included, while for bulimia nervosa, DEx decreased alongside increased functional exercise, highlighting the potential benefits of PAE in treatment.
How to address physical activity and exercise during treatment from eating disorders: a scoping review.Mathisen, TF., Hay, P., Bratland-Sanda, S.[2023]

Citations

Role of Physical Activity on Mental Health and Well-BeingAccording to general results, exercise enhances mood and self-esteem while decreasing stress tendencies, a factor known to aggravate mental and ...
Effects of combining physical activity with mindfulness on ...Interventions combining physical activity with mindfulness are effective for improving mental health and wellbeing, possibly more so than either approach alone.
Physical activity and mental health: a systematic review and ...The purpose of this study was to systematically review and synthesise evidence of all mediators and moderators of the relationship between physical activity ...
The relationship between physical activity and depression ...Regular physical activity enhances self-efficacy and reduces stress-related eating behaviors.
Bidirectional relationship of stress and affect with physical ...Physical activity and healthy eating seem to be protective against experiencing stress and negative affect as well as increase positive affect.
6.nationaleatingdisorders.orgnationaleatingdisorders.org/
NEDA | Eating Disorders Support, Awareness & RecoveryAccess support, explore resources, join community events, and take a free eating disorders screening—start your recovery journey with NEDA!
The Effects of Stress on Physical Activity and Exercise - PMCPsychological stress and physical activity (PA) are believed to be reciprocally related; however, most research examining the relationship between these ...
Exercise and stress: Get moving to manage stressExercise in almost any form can act as a stress reliever. Being active can boost your feel-good endorphins and distract you from daily worries.
When Exercise Becomes Too Much of a Good ThingWhat is exercise addiction and how closely related is it to psychiatric conditions like anorexia and bulimia? Although there is no formal ...
Medical and physiological complications of exercise for ...Individuals with eating disorders (ED) experience prolonged malnutrition, binge episodes, and compensatory behaviours that affect every ...
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