Exercise Intervention for Dense Breast Tissue
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, if you are on oral contraceptives, you may not be eligible to participate.
What data supports the effectiveness of the treatment Exercise Intervention for Dense Breast Tissue?
Is exercise intervention safe for humans?
Exercise interventions, including aerobic and resistance training, have been shown to be generally safe for humans, including those with breast cancer or at risk for breast cancer. Studies report no increased risk of lymphedema (swelling due to lymph fluid) and low rates of musculoskeletal injuries.678910
How does the exercise intervention treatment for dense breast tissue differ from other treatments?
The exercise intervention for dense breast tissue is unique because it focuses on physical activity, specifically aerobic and resistance training, to potentially influence breast density, a known risk factor for breast cancer. Unlike traditional medical treatments, this approach leverages the benefits of exercise, which has been shown to improve muscle strength and body composition in breast cancer survivors, offering a non-invasive and lifestyle-based option.511121314
What is the purpose of this trial?
This trial is studying how regular exercise affects breast tissue and blood markers in premenopausal women with dense breast tissue. These women are at higher risk for breast cancer, and exercise might help by slowing cancer cell growth and strengthening the immune system. The study aims to understand these potential benefits better.
Research Team
Jennifer Ligibel, MD
Principal Investigator
Dana-Farber Cancer Institute
Eligibility Criteria
This trial is for premenopausal women under 50 with dense breast tissue who don't exercise much (less than 90 minutes of moderate activity per week). They must be able to read English, have no history of breast cancer, and can walk at least two blocks. Women on oral contraceptives or with certain diseases that limit exercise are not eligible.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants engage in a supervised, moderate-intensity aerobic exercise program for 12 weeks
Follow-up
Participants are monitored for changes in breast tissue and blood markers after the exercise intervention
Treatment Details
Interventions
- Exercise Intervention
Find a Clinic Near You
Who Is Running the Clinical Trial?
Dana-Farber Cancer Institute
Lead Sponsor
National Cancer Institute (NCI)
Collaborator