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Exercise Training for Heart Failure
Study Summary
This trial will investigate how exercise affects molecules in people with heart failure, to see if it can be mimicked with medicine. The goal is to develop an "exercise-in-a-pill" medicine to help people with heart failure.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- I am taking medication for diabetes or to lower my blood sugar.I am not taking any drugs to specifically increase muscle size.My kidneys are not working well (GFR <60).I am between 18 and 89 years old.I am willing to join a heart health program.I haven't had treatment for autoimmune disorders in the last 6 months.My heart's pumping ability is less than 40%.I drink more than 7 (women)/14 (men) drinks weekly or have a history of binge drinking.You have been hospitalized for a mental health condition within the past year.I am taking growth hormone or similar treatments.I am currently taking monoclonal antibodies.I am currently taking medication to help me lose weight.I am currently taking narcotics or drugs that act like them.I understand and can follow the study's requirements.I have diabetes, as indicated by my medication or blood sugar levels.I am currently taking steroids or hormone therapy.I do not have any physical injuries or conditions that would stop me from completing the study.
- Group 1: Control arm: No exercise
- Group 2: Active arm: Acute exercise + 12 weeks Cardiac Rehabilitation
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Do individuals of a certain age have access to participate in this research?
"As stated by the eligibility requirements, participants in this medical trial must be aged between 18 and 89 years old."
Are there any open enrollment opportunities for this clinical trial at present?
"According to the clinicaltrials.gov resource, this medical investigation is not currently enlisting patients. Despite initially being posted on October 1st 2023 and last updated on January 13th 2023, there are still 697 other trials actively recruiting individuals at present."
Would I qualify to participate in this research endeavor?
"This investigation is recruiting 90 volunteers aged 18-89 with a diagnosis of heart failure and ejection fraction below 40%. To be eligible, they must not have been pregnant/lactating in the past year nor plan to become pregnant within the next four months. A pregnancy test will also be conducted for women of childbearing age on DXA scan day. Additionally, participants must provide informed consent and take part in cardiac rehabilitation."
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