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Moving Well for Osteoarthritis

N/A
Recruiting
Led By Iris Y Navarro Millan, MD, MSPH
Research Sponsored by Weill Medical College of Cornell University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Have at least one of these two factors: High level of anxiety as defined by the Generalized Anxiety Disorder Assessment (GAD-7) instrument (score ≥10) OR Depression, as assessed by Patient Health Questionnaire depression scale (PHQ-8) (score ≥ 10).
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months post-surgery
Awards & highlights

Study Summary

This trial will test whether a behavioral intervention can improve anxiety and depression levels for patients undergoing total knee arthroplasty.

Who is the study for?
This trial is for English-speaking individuals aged 50 or older with high anxiety or depression, who have internet access and can travel to NYC. They must be scheduled for their first knee replacement in at least 8 weeks and willing to work with a coach. Priority goes to those with low socioeconomic status or from underrepresented racial groups.Check my eligibility
What is being tested?
The study tests 'Moving Well,' a behavioral intervention aimed at reducing anxiety and depression in patients awaiting knee replacement surgery. Participants will either receive this intervention or join the control group, which involves an alternative program called 'Staying Well.'See study design
What are the potential side effects?
Since this is a behavioral intervention rather than medication, traditional side effects are not expected. However, participants may experience discomfort related to engaging in new activities or stress management techniques.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You either have severe anxiety (score of 10 or higher on GAD-7) or depression (score of 10 or higher on PHQ-8).

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months post-surgery
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months post-surgery for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in level of anxiety from baseline using the Generalized Anxiety Disorder Assessment (GAD-7)
Change in level of depression from baseline using the Patient Health Questionnaire-8 (PHQ-8)
Secondary outcome measures
Change in 30-second chair to stand test from baseline
Change in 6-minute walk test (6MWT) from baseline
Change in Timed Up and Go test (TUG) from baseline
+10 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Moving WellExperimental Treatment1 Intervention
Participants will receive weekly calls for 12 weeks (7 weeks before total knee arthroplasty surgery and 5 weeks after surgery) from a peer coach, an exercise program, and mental preparation (through positive thinking) for surgery. Participants will also receive the standard of care for patients undergoing total knee arthroplasty.
Group II: Staying WellActive Control1 Intervention
Participants will receive weekly calls for 12 weeks (7 weeks before total knee arthroplasty surgery and 5 weeks after surgery) from a research assistant. The calls will be similar in length to those in the experimental arm and will cover various health topics not related to total knee arthroplasty. Participants will also receive the standard of care for patients undergoing total knee arthroplasty.

Find a Location

Who is running the clinical trial?

Weill Medical College of Cornell UniversityLead Sponsor
1,053 Previous Clinical Trials
1,330,437 Total Patients Enrolled
Rheumatology Research FoundationOTHER
9 Previous Clinical Trials
7,271 Total Patients Enrolled
Hospital for Special Surgery, New YorkOTHER
242 Previous Clinical Trials
61,802 Total Patients Enrolled
26 Trials studying Osteoarthritis
4,295 Patients Enrolled for Osteoarthritis

Media Library

Moving Well Clinical Trial Eligibility Overview. Trial Name: NCT05217420 — N/A
Osteoarthritis Research Study Groups: Moving Well, Staying Well
Osteoarthritis Clinical Trial 2023: Moving Well Highlights & Side Effects. Trial Name: NCT05217420 — N/A
Moving Well 2023 Treatment Timeline for Medical Study. Trial Name: NCT05217420 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any opportunities to participate in this trial still available?

"By referring to the data hosted on clinicaltrials.gov, it can be determined that this medical research is actively recruiting participants. This investigation was initially listed on April 5th 2022 and last altered on April 10th 2022."

Answered by AI

What objectives does this medical investigation seek to achieve?

"The primary metric for evaluating the trial's success is a comparison of levels of depression between baseline and 6 months post-surgery, as measured by the Patient Health Questionnaire-8 (PHQ-8). Secondary assessments include an analysis of general health status via the 12-Item Short Form Survey (SF-12), self reported opioid use to manage knee pain, and overall changes in knee pain and function measuring with Knee Injury and Osteoarthritis Outcome Score (KOOS) subcales."

Answered by AI

What is the aggregate tally of participants engaging in this research endeavor?

"Affirmative. Based on the information posted on clinicaltrials.gov, this medical study is still in active recruitment mode since it was first published April 5th 2022 and most recently amended April 10th 2022. This trial seeks 100 participants from a single location."

Answered by AI

Who else is applying?

What state do they live in?
District of Columbia
New York
How old are they?
18 - 65
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
What site did they apply to?
Weill Cornell Medicine Clinical & Translational Science Center
How many prior treatments have patients received?
0
~41 spots leftby Aug 2025