196 Participants Needed

Physical Activity Prescription for Post-ACL Reconstruction Recovery

SW
Overseen ByStacey Wanlin
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Western University, Canada
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

Anterior cruciate ligament (ACL) ruptures are very common knee injuries amongst youth involved in sports and are often treated through ACL reconstruction surgeries. Unfortunately, up to 50% of individuals who undergo ACL reconstruction develop post-traumatic osteoarthritis (PTOA) in their injured knee by 20 years post-reconstruction causing pain, decreasing mobility, and impacting quality of life in young active individuals. Much remains unknown regarding the secondary prevention of PTOA, and more investigation is necessary to better understand its disease progression post-ACL reconstruction and types of conservative interventions that can prevent or delay its onset. Physical activity has improved patient-reported outcomes across many different chronic diseases including knee osteoarthritis (OA), and physical activity prescription has been shown to be an effective way to increase patients' levels of physical activity. It has not yet been heavily investigated in the context of post-ACL reconstruction, and individuals often exhibit decreased physical activity after ACL reconstruction which causes suboptimal cartilage health. Thus, physical activity prescription may improve habitual joint loading, leading to improved cartilage health and patient-reported health outcomes.

Research Team

JT

Jane Thornton, MD PhD

Principal Investigator

Western University

Eligibility Criteria

This trial is for individuals who are 7 years post-ACL reconstruction surgery and part of the STAbiLiTY study. They must have internet and smartphone access, be stable enough to engage in physical activity, willing to follow up during the study period, and communicate in English.

Inclusion Criteria

Subjects following up for 7-year visits as part of the Standard ACL Reconstruction vs ACL + Lateral Extra-Articular Tenodesis Study (STAbiLiTY)

Exclusion Criteria

I cannot or do not want to commit to the study's follow-up schedule.
I am scheduled for a second surgery during the study.
I am unable to communicate in English.
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Treatment Details

Interventions

  • Physical Activity Intervention
Trial OverviewThe trial is testing a Physical Activity Prescription (PARx) intervention aimed at improving knee health after ACL reconstruction. It investigates whether regular prescribed exercise can prevent or delay osteoarthritis by promoting better cartilage health.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: Physical Activity Prescription (PARx)Experimental Treatment1 Intervention
Patients will be prescribed technology-based physical activity programming.
Group II: Usual CareActive Control1 Intervention
Patients will receive the usual care.

Find a Clinic Near You

Who Is Running the Clinical Trial?

Western University, Canada

Lead Sponsor

Trials
270
Recruited
62,500+