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Transcranial Magnetic Stimulation
TMS for Depression (SCC-TMS Trial)
N/A
Waitlist Available
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Accompanied by at least two evidence-based augmentation therapies (Benzodiazepines do not count)
All subjects must be between 18-65 years of age
Timeline
Screening 3 weeks
Treatment Varies
Follow Up throughout study completion, 6 weeks on average
Awards & highlights
SCC-TMS Trial Summary
This trial will investigate whether it is safe to give people transcranial magnetic stimulation(TMS) at frequencies other than 10 Hz. Up to 30 people will receive TMS weekly for 6 weeks.
Who is the study for?
This trial is for adults aged 18-65 with severe Major Depressive Disorder who haven't improved after trying at least two different antidepressants and psychotherapy. Participants must be able to commit to the study schedule and visits, but can't join if they have a high seizure risk, certain neurological conditions, scalp infections, mental incapacity, or magnetic-sensitive implants near the treatment area.Check my eligibility
What is being tested?
The study tests repetitive Transcranial Magnetic Stimulation (TMS) at non-standard frequencies to treat depression. It involves an initial assessment using EEG, determining TMS settings tailored for each person, weekly mood checks, and up to 30 TMS sessions over a maximum of six weeks.See study design
What are the potential side effects?
Potential side effects of TMS may include discomfort at the stimulation site on the scalp, headache, lightheadedness, or seizures in rare cases. Most people tolerate it well without serious complications.
SCC-TMS Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am receiving two or more approved additional treatments (not including benzodiazepines).
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I am between 18 and 65 years old.
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I have tried at least 2 antidepressants without improvement.
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My condition did not improve after treatments from two different types of medication.
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I have been diagnosed with severe Major Depressive Disorder.
SCC-TMS Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ throughout study completion, 6 weeks on average
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~throughout study completion, 6 weeks on average
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in Inventory of Depressive Symptoms-Self-report scores
SCC-TMS Trial Design
1Treatment groups
Experimental Treatment
Group I: SCC-Determined TMSExperimental Treatment1 Intervention
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Who is running the clinical trial?
University of California, Los AngelesLead Sponsor
1,528 Previous Clinical Trials
10,276,841 Total Patients Enrolled
101 Trials studying Depression
48,433 Patients Enrolled for Depression
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I have been diagnosed with a psychotic disorder during my current depressive episode.I am receiving two or more approved additional treatments (not including benzodiazepines).I am at a higher risk of having seizures due to my family history, past stroke, or my current medications.I have a metal implant or device near my head that might be affected by magnets.I have a neurological condition like epilepsy or severe head trauma.I am between 18 and 65 years old.I have an infection or bad skin condition on my scalp.I have tried at least 2 antidepressants without improvement.I am able to understand and consent to participate in the study.My condition did not improve after treatments from two different types of medication.I have been diagnosed with severe Major Depressive Disorder.I have undergone psychotherapy for depression.
Research Study Groups:
This trial has the following groups:- Group 1: SCC-Determined TMS
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is this research endeavor still open to new participants?
"Clinicaltrials.gov appears to indicate that this trial has concluded, with the initial posting taking place on June 16th 2019 and the last update occurring on October 11th 2022. While no longer actively recruiting patients for this specific study, there are 1298 other clinical trials currently looking for participants."
Answered by AI
Is it possible to partake in this clinical research?
"This trial seeks to recruit 10 individuals with involutional psychosis, aged 18 - 65. To be qualified for enrollment, subjects must have failed to respond to two different classes of medications; they need a history of psychotherapy proven successful in managing MDD and the capacity/willingness to adhere to the treatment plan."
Answered by AI
Does this research project accept elderly participants?
"The minimum and maximum age parameters for this clinical trial are 18 and 65 respectively, as specified in the eligibility requirements."
Answered by AI
Who else is applying?
What site did they apply to?
UCLA Depression Research and Clinic Program
What portion of applicants met pre-screening criteria?
Met criteria
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