300 Participants NeededMy employer runs this trial

Decision Support for Opioid Use Disorder

Recruiting at 2 trial locations
LB
EM
Overseen ByEdward Melnick, MD, MHS
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Yale University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This study is stage 2, round 1 of a larger study which refines and optimizes the EMBED clinical decision support (CDS); see NCT03658642 to increase number of ED physicians following standard of care for the administration of buprenorphine to appropriate patients with opioid use disorder.

Who Is on the Research Team?

EM

Edward Melnick, MD, MHS

Principal Investigator

Yale University

Are You a Good Fit for This Trial?

Inclusion Criteria

* Emergency department patient
I am 18 years old or older.
* Moderate to severe opioid use disorder

Timeline for a Trial Participant

Preparation

Initial phase to prepare for the optimization of the clinical decision support system

4 weeks

Optimization

Conduct serial rapid-cycle randomized testing to refine the CDS interface and workflow

12 weeks
Multiple rounds of A-B testing

Evaluation

Randomized trial comparing the optimized CDS package to the original EMBED CDS

12 weeks

Follow-up

Participants are monitored for safety and effectiveness after the evaluation phase

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Refined EMBED CDS

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Refined EMBED plus nurse prompt to complete COWS placed under required documentation in EpicExperimental Treatment2 Interventions
Group II: Refined EMBED CDSActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Yale University

Lead Sponsor

Trials
1,963
Recruited
3,046,000+

National Institute on Drug Abuse (NIDA)

Collaborator

Trials
2,658
Recruited
3,409,000+