Olfactory Training Device for Loss of Smell
(SPLENDOR-OA Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if a new smell training device, ScentCare, can improve the sense of smell and overall well-being in elderly individuals with a diminished sense of smell. Participants will either use ScentCare or solve Sudoku puzzles twice daily for three months. They will visit the clinic twice to complete a smell test and some questionnaires. Ideal participants are those aged 60 or older, who speak English, have a reduced sense of smell, and have not previously tried smell training. As an unphased trial, this study offers participants the chance to contribute to innovative research that could enhance the quality of life for many.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this olfactory training device is safe for elderly patients with olfactory dysfunction?
Research has shown that olfactory training, such as that used with the ScentCare device, is generally safe. Previous studies found that this type of training can improve the sense of smell in individuals, regardless of smell loss, without significant side effects. Although detailed safety data specifically for ScentCare is lacking, olfactory training methods are typically well-tolerated. Participants in these studies did not report any major negative effects. This suggests that using ScentCare is likely safe for participants in this trial.12345
Why are researchers excited about this trial?
Researchers are excited about the ScentCare olfactory training device because it offers a novel approach to treating loss of smell by using a carefully curated selection of scents. Unlike traditional methods that might involve medications or passive scent exposure, this device actively engages users in twice-daily training with scents like Eucalyptus and Coffee, which could enhance the brain's ability to recognize and distinguish smells. With the added flexibility of using a web-based app or a booklet for guidance, it makes the training accessible and adaptable to individual preferences, potentially leading to more effective outcomes.
What evidence suggests that the ScentCare device is effective for olfactory dysfunction?
Studies have shown that smell training can help people who have lost their sense of smell. One study found that individuals with smell issues who used a smell training device like ScentCare performed better on smell tests than those who did not. In this trial, participants in the olfactory training arm will use the ScentCare device, which employs various scents such as eucalyptus and vanilla, to potentially re-activate the brain's smell pathways. Research suggests that this type of training can stimulate the brain and may aid in recovering some sense of smell. Although more studies are needed, early results appear promising for those with smell problems.12356
Who Is on the Research Team?
Nicholas Rowan, M.D.
Principal Investigator
Johns Hopkins University, Department of Otolaryngology - Head and Neck Surgery
Are You a Good Fit for This Trial?
This trial is for older adults experiencing a reduced sense of smell or Anomia. Participants must be willing to use the ScentCare device or solve Sudoku puzzles twice daily for three months and attend two clinic visits.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants use ScentCare or solve Sudoku puzzles twice daily for 3 months
Follow-up
Participants are monitored for changes in olfaction and quality of life after treatment
What Are the Treatments Tested in This Trial?
Interventions
- ScentCare
Find a Clinic Near You
Who Is Running the Clinical Trial?
Johns Hopkins University
Lead Sponsor