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Radiation Therapy After Systemic Therapy for Breast Cancer
Study Summary
This trial is testing whether eliminating surgery and just using radiation therapy after systemic therapy works well in treating patients with HER2 positive or triple negative breast cancer.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am a woman over 40 with a specific type of early-stage breast cancer, interested in hormone therapy and breast-saving treatment, with no prior breast radiation.I have advanced breast cancer with signs of spreading and no current pregnancy.I am a woman over 30 with early-stage, HER2 positive breast cancer or over 50 with triple-negative breast cancer, seeking breast conserving therapy.I am a woman over 40 with a specific type of breast cancer, wanting to save my breast, and have treated any other cancers.My breast cancer is at stage T2-T3 or clinically at stage T4.
- Group 1: Cohort C
- Group 2: Cohort A
- Group 3: Cohort B
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are researchers enrolling people in this clinical trial at this time?
"This trial is still recruiting patients, with the latest update having been on September 27th, 2022. The original posting date was January 20th, 2017."
Are other research hospitals in Canada also administering this trial?
"Patients are being recruited for this study at Mayo Clinic in Rochester, Minnesota; M D Anderson Cancer Center in Houston, Texas; Baptist MD Anderson Cancer Center in Jacksonville, Florida; and six additional sites."
How many total enrollees are in this clinical research program?
"To run this study successfully, we need 120 patients that fit the given inclusion criteria. Some of the places where patients can participate in this trial include Mayo Clinic in Rochester, Minnesota and M D Anderson Cancer Center in Houston, Texas."
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