Conditioning and active avoidance paradigm (CAAP) for Anxiety disorder

N/A

Recruiting

Led By Mohammed Milad, PhD

Research Sponsored by The University of Texas Health Science Center, Houston

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up immediately after the memory recall phase (day 2 about 1 day 18 minutes after start of memory recall phase)

Awards & highlights

Study Summary

This trial aims to study brain activity related to fear conditioning, avoidance learning, and memory recall. Researchers will investigate how different brain waves and connections in the brain are involved in these processes. They will also

Who is the study for?

This trial is for individuals with an anxiety disorder. Participants should be able to undergo fear conditioning and active avoidance tasks while their brain activity is monitored using EEG. Specific inclusion or exclusion criteria are not provided, but typically participants must be healthy enough for the procedures.Check my eligibility

What is being tested?

The study investigates how certain brain wave patterns (ERPs and EROs) relate to learning about fear and making decisions to avoid things that cause fear. It uses a special task called CAAP while recording brain activity with EEG, looking at memory recall related to fear and avoidance.See study design

What are the potential side effects?

Since this study involves non-invasive monitoring of brain activity through EEG during specific tasks, there are minimal side effects expected. Some participants might experience discomfort from wearing the EEG cap or stress from the fear-conditioning exercises.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ immediately after the memory recall phase (day 2 about 1 day 18 minutes after start of memory recall phase).

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~immediately after the memory recall phase (day 2 about 1 day 18 minutes after start of memory recall phase).

This trial's timeline: 3 weeks for screening, Varies for treatment, and immediately after the memory recall phase (day 2 about 1 day 18 minutes after start of memory recall phase). for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Number of participants who had higher event-related potentials (ERPs) in response to CS+ categories relative to CS- categories, as assessed by electroencephalogram (EEG) during the avoidance learning phase

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Trial Design

1Treatment groups

Experimental Treatment

Group I: Conditioning and active avoidance paradigm (CAAP)Experimental Treatment1 Intervention

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Who is running the clinical trial?

The University of Texas Health Science Center, HoustonLead Sponsor

904 Previous Clinical Trials

320,810 Total Patients Enrolled

Mohammed Milad, PhDPrincipal InvestigatorThe University of Texas Health Science Center, Houston

2 Previous Clinical Trials

286 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are patients currently being sought to participate in this clinical trial?

"As per information on clinicaltrials.gov, the present medical trial is not open for recruitment. Originally posted on January 30th, 2024 and most recently revised on January 25th, 2024, this study has concluded patient enrollment. However, it's worth noting that one additional clinical trial is actively recruiting participants presently."

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