Diuretic Tuner App for Chronic Kidney Disease
Trial Summary
What is the purpose of this trial?
This purpose of this study is to determine the effectiveness of a mobile phone application in helping to control body swelling in patients with kidney problems. The application will help in the day to day adjustments in diuretic medication dosing. Participants in this study will have an application loaded on to their mobile phone by the study team and be taught how to use it over a 2 hour visit. Participants will need to check their blood pressure and weight daily and enter this information into the mobile phone application every day. Participants will need to follow daily instructions in their medication dosing provided by the application. There will be periodic blood testing. This will happen at 2 weeks, 90 days, and up to 4 other times if necessary. At the end of the study there is a 2 hour study visit during which participants will answer a survey. The total length of the study is 90 days.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications. However, you will need to follow daily instructions for diuretic medication dosing provided by the mobile app.
What data supports the effectiveness of the Diuretic Tuner App for Chronic Kidney Disease?
Is the Diuretic Tuner App safe for people with chronic kidney disease?
How is the Diuretic Tuner drug unique for treating chronic kidney disease?
The Diuretic Tuner app combines different types of diuretics (water pills) like loop, thiazide, and potassium-sparing diuretics, which can be tailored to individual needs, potentially offering a more personalized approach to managing fluid balance and blood pressure in chronic kidney disease patients compared to standard treatments.3481011
Eligibility Criteria
This trial is for adults with severe kidney disease or nephrotic syndrome who have swelling due to fluid overload. They must be able to use a smartphone app, weigh between 100-300 lbs, and not be at immediate risk of needing dialysis or have life-threatening low potassium or sodium levels.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants use the Diuretic Tuner mobile application to adjust diuretic dosing based on daily weight and blood pressure inputs
Follow-up
Participants are monitored for safety and effectiveness after treatment, including a survey on tool usability
Treatment Details
Interventions
- Diuretic Tuner
Diuretic Tuner is already approved in European Union, United States, Canada, Japan, China, Switzerland for the following indications:
- High Blood Pressure
- Edema
- Heart Failure
- Chronic Kidney Disease
- Liver Disease
- High Blood Pressure
- Edema
- Heart Failure
- Chronic Kidney Disease
- Liver Disease
- High Blood Pressure
- Edema
- Heart Failure
- Chronic Kidney Disease
- Liver Disease
- High Blood Pressure
- Edema
- Heart Failure
- Chronic Kidney Disease
- Liver Disease
- High Blood Pressure
- Edema
- Heart Failure
- Chronic Kidney Disease
- Liver Disease
- High Blood Pressure
- Edema
- Heart Failure
- Chronic Kidney Disease
- Liver Disease
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Texas Southwestern Medical Center
Lead Sponsor