VR Training for Hemispatial Neglect

(Neglex01 Trial)

MO
Overseen ByMarkey Olson, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Markey Olson
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new virtual reality (VR) training system to assist individuals with hemispatial neglect, a condition where people ignore one side of their environment after a brain injury, such as a stroke. The VR headset aims to enhance diagnosis and therapy by measuring how quickly participants respond to visual cues. The goal is to make treatment more effective and accessible, potentially enabling individuals to practice independently. Suitable candidates for this trial include those who have experienced a brain injury affecting one side, retain some hand control for using a VR controller, and have clear vision. As an unphased trial, this study provides a unique opportunity to contribute to innovative research that could transform rehabilitation methods.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this VR training is safe for neglect therapy?

Research has shown that using virtual reality (VR) for training is generally safe for treating unilateral spatial neglect, a condition often seen in stroke patients. Past studies have demonstrated that VR can improve symptoms without causing major problems. Many studies have found that both immersive VR, where users feel inside the virtual world, and non-immersive VR, where they do not, are well-accepted by patients.

For example, one study found VR effective and safe for helping stroke patients with attention issues. Another study confirmed that using immersive VR systems to assess and treat neglect was safe, with no serious side effects reported.

This suggests that the VR training in the trial is likely to be safe and well-tolerated, with a low risk of severe side effects. However, discussing any concerns with the trial team before joining is always important.12345

Why are researchers excited about this trial?

Most treatments for hemispatial neglect, like cognitive therapy and eye patching, focus on retraining the brain to pay attention to the neglected side using traditional, hands-on methods. But VR Neglect Training is different because it uses virtual reality to immerse patients in a controlled environment that actively engages their spatial awareness. This innovative approach allows for customizable scenarios that can adapt to each patient's progress, potentially offering a more engaging and effective rehabilitation experience. Researchers are excited about this treatment because it could revolutionize how we approach cognitive rehabilitation by providing a more interactive and responsive form of therapy.

What evidence suggests that this VR training is effective for hemispatial neglect?

Studies have shown that virtual reality (VR) training can significantly alleviate symptoms of neglect. One study found that individuals using VR improved more than those who did not. Research also indicates that both fully immersive and non-immersive VR effectively treat unilateral spatial neglect. Previous patients have found VR training more effective than traditional cognitive exercises. Overall, VR training offers a promising and engaging option for treating neglect and may outperform other methods. Participants in this trial will receive VR Neglect Training to further evaluate its effectiveness.12678

Are You a Good Fit for This Trial?

This trial is for adults over 18 with a neurological injury (like stroke, tumor, or trauma) affecting one side of the brain. They must have at least one hand able to use a controller and intact visual fields. Participants need cognitive ability to follow simple instructions but can't join if they have injuries on both sides of the brain, severe visual issues besides neglect, or can't consent.

Inclusion Criteria

At least one hand that retains dexterity enough to use a controller to extinguish the visual stimulus
Visual fields intact
I am over 18 and have had a neurological injury such as a stroke, tumor, or trauma.
See 2 more

Exclusion Criteria

Bilateral symptomatic injury
Inability to consent or to comply with study
Blindness or severe visual deficits other than neglect

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in a mixed-reality visual attention task using a VR headset to improve neglect diagnosis and therapeutic intervention

6 months
Regular sessions as per study protocol

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • VR Neglect Training
Trial Overview The study tests a mixed-reality visual attention task using virtual reality (VR) for diagnosing and rehabilitating hemispatial neglect. It aims to see if this VR system is safe and practical for detecting neglect and improving patients' attention in their neglected field through neuromodulatory training.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: TreatmentExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Markey Olson

Lead Sponsor

Trials
1
Recruited
90+

Citations

The Effect of Virtual Reality Training on Unilateral Spatial ...This study observed that the VR group showed a significant improvement in neglect compared to the control group when the virtual reality program was applied to ...
The Effects of Virtual Reality-based Training for ...This study aims to investigate the effectiveness and underlying recovery mechanisms of a virtual reality-based training program for the ...
Virtual reality rehabilitation for unilateral spatial neglectVirtual reality has been shown to improve symptoms of unilateral spatial neglect. •. Non-immersive, semi-immersive and immersive VR protocols are all effective.
Feasibility of hemispatial neglect rehabilitation with virtual ...Previous studies have demonstrated that VET is more effective in improving symptoms of neglect than usual cognitive training (Antonucci et al., ...
Feasibility of hemispatial neglect rehabilitation with virtual ...Hemispatial neglect (HSN) was diagnosed using a virtual reality-based test (FOPR test) that explores the field of perception (FOP) and field ...
Virtual Reality Attention Training in Stroke PatientsA virtual reality (VR) behavioral training for the attention deficits characteristic of patients with hemispatial neglect was developed. Patients are ...
the immersive virtual road-crossing taskiVRoad is an immersive, naturalistic virtual reality task that can measure clinically relevant behavioral variance and identify discrete neglect symptoms.
immersive virtual reality to assess unilateral spatial neglect ...Several studies have demonstrated the safe use of an immersive VR ... A virtual reality assessment and training system for unilateral neglect.
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