Contact Lens Wear for Fuchs' Dystrophy
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this study is to determine the difference in the cornea's response to contact lens placement between healthy and unhealthy eyes. The amount of corneal swelling (corneal thickness) between normal and FECD patients before and after a stress test will be measured and compared.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is wearing contact lenses generally safe for humans?
Contact lenses are generally safe for humans, but the risk of complications varies by type. Extended-wear soft lenses have a higher risk of complications like corneal ulcers compared to daily-wear lenses. Gas permeable lenses allow more oxygen to reach the eye, making them safer for prolonged use.12345
How does contact lens wear differ from other treatments for Fuchs' Dystrophy?
Contact lens wear for Fuchs' Dystrophy is unique because it can help manage symptoms by providing a protective barrier and promoting comfort, especially after surgical procedures. Unlike other treatments, contact lenses can also help with irregular astigmatism by providing a stable surface for the eye, which is not typically addressed by standard medical or surgical treatments.26789
What data supports the effectiveness of the treatment of wearing contact lenses for Fuchs' Dystrophy?
Research suggests that contact lenses, including soft and rigid types, can help manage various corneal conditions by improving comfort and visual performance. For example, soft contact lenses have been beneficial in managing corneal erosions and promoting healing after surgery, while rigid lenses can help with irregular astigmatism, which may be relevant for Fuchs' Dystrophy.610111213
Are You a Good Fit for This Trial?
This trial is for individuals with Fuchs endothelial corneal dystrophy (FECD) who are scheduled for a corneal transplant within the next 6 months. Participants should not have had previous eye surgery, contact lens intolerance, or other ocular diseases like glaucoma.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Stress Test
Participants wear an FDA-approved contact lens for three hours to induce corneal swelling
Recovery Monitoring
Participants are monitored for corneal recovery after the stress test
Follow-up
Participants are monitored for safety and effectiveness after the stress test
What Are the Treatments Tested in This Trial?
Interventions
- Wearing of contact lens
Find a Clinic Near You
Who Is Running the Clinical Trial?
Massachusetts Eye and Ear Infirmary
Lead Sponsor