← Back to Search

Radiation Therapy

Motion-Corrected Cone-Beam CT for Lung Cancer

N/A

Waitlist Available

Led By Michael Lovelock, PhD

Research Sponsored by Memorial Sloan Kettering Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Karnofsky Performance Status ≥ 60%

Age ≥ 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 year

Awards & highlights

Study Summary

This trial is testing a new computer program that may help doctors better locate tumors in cone-beam CT scans. The effects of this program on patients and cancer treatment will be studied. Additionally, the program will be compared to radio signals in tracking markers in images.

Who is the study for?

This trial is for adults over 18 with confirmed lung malignancies suitable for radiation therapy, who are planning to undergo such treatment. They must have a visible part of the tumor on CT scans and be in relatively good health (Karnofsky Performance Status ≥ 60%). They should be able to have small markers placed in their lungs via bronchoscopy.Check my eligibility

What is being tested?

The study is testing a new computer program that aims to reduce blurring on cone-beam CT scans used during lung cancer treatments. It will compare how well this program locates tumors against another method using radio signals to track implanted markers during stereotactic body radiation treatments.See study design

What are the potential side effects?

Potential side effects may include complications from bronchoscopic implantation like infection or bleeding, reactions related to anesthesia or sedation, and discomfort from the placement of electromagnetic transponders.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I can care for myself but may need occasional help.

Select...

I am 18 years old or older.

Select...

I am planning to undergo radiation therapy for lung cancer or cancer that has spread to the lung.

Select...

My cancer is confirmed and can be treated with chest radiation.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

successful Calypso transponder implantation

Trial Design

1Treatment groups

Experimental Treatment

Group I: Patients with lung cancerExperimental Treatment3 Interventions

Physician evaluation of patient setup accuracy will be performed using all available images and adjustments will be made as per standard practice. In addition, a respiration motion-corrected CBCT (daily for SBRT, weekly for standard fractionation) will be used to confirm the accuracy of Calypso-based setup. Patients will return for follow up at 3,6, 9, 12, 15, 18, 21 and 24 months (+/- 4 weeks) following completion of radiation therapy. The following assessments will be performed at these visits: history and physical exam, diagnostic CT chest, and toxicity assessment.

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

Memorial Sloan Kettering Cancer CenterLead Sponsor

1,933 Previous Clinical Trials

585,603 Total Patients Enrolled

Michael Lovelock, PhDPrincipal InvestigatorMemorial Sloan Kettering Cancer Center

1 Previous Clinical Trials

25 Total Patients Enrolled

Zhang Peng, PhDPrincipal InvestigatorMemorial Sloan Kettering Cancer Center

Media Library

Stereotactic Body Radiation Treatments (Radiation Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT02434809 — N/A

Lung Cancer Research Study Groups: Patients with lung cancer

Lung Cancer Clinical Trial 2023: Stereotactic Body Radiation Treatments Highlights & Side Effects. Trial Name: NCT02434809 — N/A

Stereotactic Body Radiation Treatments (Radiation Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02434809 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there still capacity for participants in this experiment?

"The trial's listing on clinicaltrials.gov confirms that it is not presently accepting patients; the study was first posted back in April 2015 and last updated May 23rd 2022. However, there are 2,762 other trials actively seeking participants at this time."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Respiratory Motion-Corrected Cone-Beam CT and Intratreatment Gating Based on Electromagnetic Transponders to Reduce Target Position Uncertainty in Radiation Treatment of Lung Malignancies

2015. "Respiratory Motion-Corrected Cone-Beam CT and Intratreatment Gating Based on Electromagnetic Transponders to Reduce Target Position Uncertainty in Radiation Treatment of Lung Malignancies". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02434809.

All > Cte