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Behavioral Intervention

Cycling with Cognitively Stimulating VR for Multiple Sclerosis (PACE-MS Trial)

N/A

Recruiting

Led By Carly Wender, PhD

Research Sponsored by Kessler Foundation

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Confirmed MS diagnosis by a neurologist

Moderate self-report mobility disability

Timeline

Screening 3 weeks

Treatment Varies

Follow Up immediately before the single bout of cycling and 5 minutes after the single bout of cycling.

Awards & highlights

PACE-MS Trial Summary

This trial is comparing the effects of different types of virtual reality during cycling exercise on thinking speed in people with multiple sclerosis.

Who is the study for?

This trial is for English-speaking individuals with a confirmed MS diagnosis by a neurologist, who have been free of relapses and steroids for at least 30 days, and report moderate mobility disability. It excludes those with other neurological disorders or uncontrolled psychiatric conditions, contraindications to exercise, cognition-impacting medications use (like steroids), current pregnancy, severe cognitive impairment, high motion sickness likelihood or regular cyclists.Check my eligibility

What is being tested?

The PACE-MS trial aims to compare the effects on processing/thinking speed in people with MS when they participate in cycling exercises combined with different types of virtual reality experiences.See study design

What are the potential side effects?

While specific side effects are not listed for this intervention involving exercise and virtual reality, participants may experience general exercise-related discomforts such as muscle soreness or fatigue. Virtual reality may cause dizziness or nausea especially in those prone to motion sickness.

PACE-MS Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have been diagnosed with MS by a neurologist.

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I have some difficulty moving around on my own.

PACE-MS Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline visit only.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline visit only.

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline visit only. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Modified Flanker Task (MFT)

Secondary outcome measures

Baseline Symbol Digit Modalities Test (SDMT)

Baseline mobility disability

PACE-MS Trial Design

3Treatment groups

Experimental Treatment

Active Control

Group I: Cycling with Visually Stimulating VRExperimental Treatment1 Intervention

Cycling with virtual reality where I only have to look at the environment while I cycle.

Group II: Cycling with Cognitively Stimulating VRExperimental Treatment1 Intervention

Cycling with virtual reality where I have to complete a thinking task while cycling in the virtual environment.

Group III: Cycling AloneActive Control1 Intervention

Cycling alone, with no virtual reality.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Kessler FoundationLead Sponsor

174 Previous Clinical Trials

10,714 Total Patients Enrolled

32 Trials studying Multiple Sclerosis

1,593 Patients Enrolled for Multiple Sclerosis

Consortium of Multiple Sclerosis CentersOTHER

8 Previous Clinical Trials

50,135 Total Patients Enrolled

8 Trials studying Multiple Sclerosis

50,135 Patients Enrolled for Multiple Sclerosis

Carly Wender, PhDPrincipal InvestigatorKessler Foundation

1 Previous Clinical Trials

78 Total Patients Enrolled

1 Trials studying Multiple Sclerosis

78 Patients Enrolled for Multiple Sclerosis

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are new participants currently being welcomed to enroll in this trial?

"According to the information provided on clinicaltrials.gov, this specific study is not currently actively seeking participants. The trial was initially posted on January 1, 2024, and last updated on January 3, 2024. However, it's worth noting that there are presently 518 other trials actively searching for eligible candidates at this time."

Answered by AI

Is it possible for me to participate in this clinical trial?

"To be eligible for participation in this research study, individuals must have a confirmed diagnosis of multiple sclerosis and fall within the age range of 18 to 65 years. The trial aims to enroll approximately 24 participants."

Answered by AI

Are individuals who are 60 years of age and older eligible to participate in this medical study?

"Applicants who meet the eligibility criteria for this clinical trial must fall within the age range of 18 to 65. It is worth noting that there are a total of 35 studies specifically targeting individuals under the age of 18, while there are 375 studies catering to those over the age of 65."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Effects of Cycling and Virtual Reality on Thinking Speed in Persons With MS (PACE-MS)

2024. "Effects of Cycling and Virtual Reality on Thinking Speed in Persons With MS (PACE-MS)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06191380.