Study Summary
This trial will test if losartan can improve cardiopulmonary outcomes in people with pre-COPD caused by long-term exposure to secondhand tobacco smoke. The trial is double-blind, meaning neither the participants nor the researchers will know who is taking losartan or the placebo until the trial is over.
- High Blood Pressure
- Cardiovascular Disease
Treatment Effectiveness
Effectiveness Progress
Study Objectives
4 Primary · 15 Secondary · Reporting Duration: At baseline assessment (V1); 4th week of V2 (placebo/losartan) treatment period; and 4th week of V3 (placebo/losartan) treatment period
Trial Safety
Safety Progress
Side Effects for
Trial Design
2 Treatment Groups
Placebo then Losartan
1 of 2
Losartan then Placebo
1 of 2
Experimental Treatment
100 Total Participants · 2 Treatment Groups
Primary Treatment: Losartan · Has Placebo Group · Phase 4
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · All Participants · 4 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| California | 100.0% |
What portion of applicants met pre-screening criteria?
| Met criteria | 100.0% |
Frequently Asked Questions
Is the recruitment process for this study still open?
"Clinicaltrials.gov reports that this medical investigation is actively seeking participants, with the trial first uploaded on March 30th 2021 and amended as recently as April 29th 2022." - Anonymous Online Contributor
What is the total number of participants in this trial?
"Affirmative. Clinicaltrials.gov's records show that this clinical trial, initially listed on March 30th 2021, is actively recruiting participants from a single location and requires 100 patients in total." - Anonymous Online Contributor
Has the Food and Drug Administration approved Losartan for medical use?
"The existing data detailing Losartan's safety classifies it as a 3, considering that this is Phase 4 of the clinical trial process and therefore has been approved." - Anonymous Online Contributor
What is the ultimate aim of this clinical research?
"This clinical trial will be conducted over a 1-day baseline period and aims to measure the Change in Mean Peak Oxygen Consumption (VO2) Level. Secondary outcomes that are being assessed include changes in maximum oxygen pulse, diastolic blood pressure slope, and systolic blood pressue slope." - Anonymous Online Contributor
What ailments does Losartan commonly address?
"Losartan may be prescribed to those suffering from hypotension, as well as various other maladies including diabetic nephropathy, left ventricular hypertrophy, and proteinuria." - Anonymous Online Contributor