Static Magnetic Helmet for Migraine

Overseen By Marco L Loggia, PhD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Marco Loggia

Must not be taking: Opioids, CGRP medications, Benzodiazepines

Disqualifiers: Seizures, Schizophrenia, Bipolar, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 3

Duration: 3 weeks

What You Need to Know Before You Apply

What is the purpose of this trial?

We are conducting this research in individuals with migraines to find out if a daily magnet helmet application could alter migraine-related brain inflammation. Outcomes will be assessed through examining any changes in Translocator Protein (TSPO) binding on Positron Emission Tomography-Computed Tomography (PET-CT) imaging both before and after the magnet helmet intervention period. Additionally, patient-reported migraine symptoms will be measured using validated questionnaires administered during the four-week pre- and post- intervention monitoring periods.

Are You a Good Fit for This Trial?

This trial is for adults who experience migraines. People with certain medical conditions or other reasons that could interfere with the study may not be able to participate.

Inclusion Criteria

Willingness to adhere to daily intervention sessions and complete study procedures

I am between 18 and 65 years old.

Able to give written consent in English

Exclusion Criteria

Major systemic illness or unstable medical and/or psychiatric condition that could compromise protocol adherence

Participation in other concurrent therapeutic trials

I have another health condition that could affect the study results.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week

1 visit (in-person)

Pre-intervention Monitoring

Participants complete questionnaires and undergo initial imaging scans

4 weeks

1 visit (in-person)

Treatment

Participants wear the magnet helmet for 20 minutes daily

3 weeks

At-home intervention

Post-intervention Monitoring

Participants complete questionnaires and undergo follow-up imaging scans

4 weeks

1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Static Magnetic Helmet

Trial Overview

The study tests whether wearing a helmet that produces a static magnetic field every day can reduce brain inflammation linked to migraines. Changes are measured by brain scans and migraine symptom questionnaires before and after using the helmet.

How Is the Trial Designed?

Group I: Patients with Migraine Experimental Treatment 1 Intervention

This arm will undergo the 21-day at-home self-administered non-drug intervention

Who Is Running the Clinical Trial?

Marco Loggia

Lead Sponsor

Trials

1

Recruited

90+