CBD for Breast Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores the effects of CBD, a compound from the cannabis plant, as a treatment for invasive breast cancer. Participants will take either a low or high dose of oral CBD or a placebo, which has no therapeutic effect, before their scheduled surgery. Researchers aim to determine how CBD might influence cancer cells in a short time frame. The trial suits women with confirmed invasive breast cancer (stages I to III) who are scheduled for surgery and can manage the trial's requirements. As a Phase 1 trial, the research focuses on understanding how the treatment works in people, offering participants the opportunity to be among the first to receive this new treatment.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research has shown that taking CBD orally has been safe in past studies. For example, studies with women who have advanced breast cancer found that CBD was safe and even helped reduce anxiety, with participants experiencing no major safety issues.
In another study, CBD proved safe for women anxious about medical scans, with no serious side effects reported. This suggests that CBD is generally well-tolerated. While the current trial is in an early stage, existing evidence from other studies is promising regarding the safety of CBD in humans.12345Why do researchers think this study treatment might be promising for breast cancer?
Unlike traditional treatments for breast cancer, which often include surgery, chemotherapy, and radiation, the CBD oral treatment offers a novel approach by utilizing cannabidiol, a compound derived from the cannabis plant. Researchers are excited about CBD because it has a different mechanism of action; it interacts with the body's endocannabinoid system, which may help in managing pain and inflammation associated with cancer. Additionally, the oral delivery method makes it potentially more convenient and less invasive than other treatment modalities. This exploration of CBD could open new avenues for symptom relief and support in cancer care.
What evidence suggests that CBD Oral might be an effective treatment for breast cancer?
Research has shown that CBD (cannabidiol) might help fight breast cancer. Studies suggest that CBD can slow cancer cell growth, induce cell death, and prevent the cancer from spreading. In one study, CBD significantly shrank breast cancer tumors. Another study found that CBD can lower levels of a protein called ID1, which aids in cancer spread. This trial will evaluate the effects of CBD Oral, administered at either 175mg or 350mg twice daily, compared to a placebo control. These findings suggest that CBD could be a promising treatment for breast cancer by directly targeting cancer cells.24678
Are You a Good Fit for This Trial?
Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either CBD or placebo orally twice daily for 5-56 days
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- CBD Oral
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
CBD Oral 175mg or 350mg twice daily for 5-56 days
Placebo control Oral twice daily for 5-56 days
Find a Clinic Near You
Who Is Running the Clinical Trial?
Medical University of South Carolina
Lead Sponsor
Citations
NCT06148038 | CBD for Breast Cancer Primary Tumors
In a clinical study's protocol, the planned outcome measure that is the most important for evaluating the effect of an intervention/treatment. Most clinical ...
Cannabidiol as a novel therapeutic agent in breast cancer
Results: CBD demonstrated significant anticancer effects, including induction of apoptosis, inhibition of cell proliferation, suppression of ...
Cannabidiol for Scan-Related Anxiety in Women With ...
Conclusions and Relevance The findings of this randomized clinical trial show that CBD can be used safely in women with advanced breast cancer ...
Cannabidiol (CBD) as a promising anti-tumor agent
CBD demonstrates multi-target anti-tumor effects, including inhibiting proliferation, inducing apoptosis, suppressing metastasis, and remodeling ...
5.
aacrjournals.org
aacrjournals.org/mct/article/10/7/1161/91099/Cannabidiol-Induces-Programmed-Cell-Death-inCannabidiol Induces Programmed Cell Death in Breast ...
A recent study reports that CBD inhibits breast cancer growth (11) and downregulates ID1, a regulator of metastasis in breast cancer cell lines (12).
Cannabidiol as a novel therapeutic agent in breast cancer
CBD demonstrated significant anticancer effects, including induction of apoptosis, inhibition of cell proliferation, suppression of metastasis, ...
Cannabidiol Safe, May Lower Anxiety in Advanced Breast ...
Cannabidiol is safe and may reduce anxiety levels for patients with advanced breast cancer and baseline clinical anxiety.
8.
renalandurologynews.com
renalandurologynews.com/news/cannabidiol-safe-may-lower-anxiety-in-advanced-breast-cancer/Cannabidiol Safe, May Lower Anxiety in Advanced Breast ...
Cannabidiol is safe and may reduce anxiety levels in patients with advanced breast cancer 2 to 4 hours after ingestion.
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