Physical Activity for HIV

Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Georgetown University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to assess how increasing physical activity, specifically walking, affects health markers like blood sugar and cholesterol in people with or without HIV. Participants will gradually increase their walking over six months as part of a Home Based Physical Activity Intervention. Ideal candidates for this trial include individuals with metabolic syndrome or related risk factors, a BMI of 30 or higher, and those not currently exercising regularly. As an unphased trial, this study offers a unique opportunity to contribute to research that could enhance health outcomes for many.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your healthcare provider.

What prior data suggests that this physical activity intervention is safe for people with and without HIV?

Research shows that exercise at home is safe for adults living with HIV. Studies have found that home exercise programs can improve health by lowering blood sugar and cholesterol levels. These programs are generally easy to follow and rarely cause problems or side effects. Some studies focus on people with HIV, while others include those without it, and both show similar safety results. Overall, increased activity at home appears to be a safe way to enhance health.12345

Why are researchers excited about this trial?

Researchers are excited about the home-based physical activity intervention for HIV because it offers a unique and accessible approach to managing the condition. Unlike traditional treatments, which often focus on antiretroviral medications to control the virus, this intervention emphasizes increasing physical activity in the comfort of one's home. This approach not only promotes overall health and well-being but also empowers participants to manage their condition through lifestyle changes, potentially reducing the need for frequent clinical visits. The focus on personalized, home-based exercise routines makes it an innovative option that could complement existing medical treatments.

What evidence suggests that this physical activity intervention is effective for improving metabolic parameters in people with and without HIV?

Research shows that exercising at home can benefit people living with HIV. Studies have found that these activities can boost fitness levels, improve heart and lung health, change body shape, increase strength, and enhance quality of life. For instance, one study found that exercising independently at home or in the community is safe and can help reduce body fat and improve overall well-being. However, some studies did not find a significant increase in moderate exercise levels, though there were signs of possible benefits. Overall, exercising at home could improve health for those with HIV. Participants in this trial will engage in a home-based physical activity intervention to explore these potential benefits further.24567

Are You a Good Fit for This Trial?

This trial is for adults aged 18 or older with a BMI of 30 or more, living with or without HIV and having metabolic syndrome or its risk factors. Participants must be able to walk for at least 10 minutes without physical limitations and provide informed consent. Medical clearance may be required.

Inclusion Criteria

Can provide evidence of medical clearance by healthcare provider, if required before or during the study
I am 18 years old or older.
Persons living with or without HIV
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants progressively increase physical activity to approximately 10,000 steps/day over a 6-month period, monitored by a physical activity monitor

6 months
5 visits (in-person)

Follow-up

Participants are monitored for changes in metabolic parameters and body composition at 3-month and 6-month follow-up visits

6 months
2 visits (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • Home Based Physical Activity Intervention
Trial Overview The study tests how a home-based walking program affects blood sugar, cholesterol, and body measurements in people with/without HIV over six months. The goal is to progressively increase physical activity as tolerated.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Intervention ArmExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Georgetown University

Lead Sponsor

Trials
355
Recruited
142,000+

Citations

Effectiveness of self-managed home and community exercise ...Studies on exercise interventions in PLWH record dropout rates as high as 29% [27]. While professional supervision appears to reduce dropout [27], exercising ...
2.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/35735412/
Home-based interventions to promote physical activity for ...We conclude HBI (aerobic and/or resistance exercises) may contribute to improve PA and/or cardiorespiratory fitness, body composition, strength and QoL of PLH.
A systematic review and meta-analysis evaluating the ...Home or community exercise can improve physical activity, body fat and quality of life for adults with HIV. •. Self-directed home or community exercise is safe ...
Results of a nine month home-based physical activity ...Results show that the home-based PA intervention was not successful in increasing the total amount of MPA for PLWHA. However there was a trend (p=0.08) of ...
Full article: The effects of behavioral change interventions ...Results of a nine month home-based physical activity intervention for older people living with HIV. International Journal of Clinical Trials ...
6.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/40289036/
Exercise Interventions Conducted Among Individuals with Co ...Evidence from this systematic review supports the use of exercise to improve a variety of health outcomes among PWH with unhealthy substance use.
Study Details | NCT01377064 | Home-based Exercise for ...This study will test the feasibility of an at-home exercise program for PLWHA and prepare for a full-scale intervention study, which may lead to a reduction in ...
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