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Cutting-Edge Diagnostic Technologies for Youth Psychosis

N/A

Recruiting

Led By Aaron Besterman, MD

Research Sponsored by Rady Pediatric Genomics & Systems Medicine Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 years

Awards & highlights

Study Summary

This trialwill use cutting-edge technology to better understand the causes and treatments of psychotic symptoms or schizophrenia in 15 children & adolescents. It may lead to new treatments for future patients.

Who is the study for?

This trial is for children and adolescents with first break psychosis admitted to Rady Children's Hospital. Biological parents can also join for genetic testing. It excludes those who've had prior genome sequencing, cannot give consent, or are protected research subjects.Check my eligibility

What is being tested?

The study uses advanced genomic and protein sequencing technologies to understand the genetic and immune factors in youth with psychosis. The goal is to find new causes of psychosis that could lead to better treatments.See study design

What are the potential side effects?

Since this trial involves diagnostic procedures rather than medications, typical drug side effects are not expected. However, there may be some discomfort or risks associated with blood draws or other sample collection methods used.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Brain

Trial Design

1Treatment groups

Experimental Treatment

Group I: Enrollees - WGSExperimental Treatment2 Interventions

These participants will be subject to whole genome sequencing and Phage ImmunoPrecipiation sequencing (PhIP-Seq) to identify genetic changes and novel antibodies associated with psychosis.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Rady Pediatric Genomics & Systems Medicine InstituteLead Sponsor

8 Previous Clinical Trials

213,838 Total Patients Enrolled

Aaron Besterman, MDPrincipal InvestigatorRady Pediatric Genomics & Systems Medicine Institute

1 Previous Clinical Trials

150 Total Patients Enrolled

Media Library

Enrollees - WGS Clinical Trial Eligibility Overview. Trial Name: NCT05457140 — N/A

Psychosis Research Study Groups: Enrollees - WGS

Psychosis Clinical Trial 2023: Enrollees - WGS Highlights & Side Effects. Trial Name: NCT05457140 — N/A

Enrollees - WGS 2023 Treatment Timeline for Medical Study. Trial Name: NCT05457140 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the total number of individuals participating in this clinical trial?

"Affirmative. Per the clinicaltrials.gov page, this research endeavour is currently seeking volunteers to partake in its investigation. The trial was first announced on October 10th 2022 and has been recently updated on October 24th 2022; consequently, 15 individuals are being sought from a single site for enrolment purposes."

Answered by AI

To whom is this clinical experimentation accessible?

"To qualify for this clinical trial, applicants must be diagnosed with psychosis and fall between the age of 7-17. There are 15 slots available in total."

Answered by AI

Are there any unfilled positions for participants in this trial?

"Affirmative, clinicaltrials.gov data confirms that the trial is actively recruiting participants since it was first posted on October 10th 2022. The study requires 15 patients from a single medical centre and has most recently been updated on October 24th 2022."

Answered by AI

Does the research permit seniors aged seventy and above to join?

"Eligibility requirements for this trial are quite specific, with only minors aged between 7 and 17 permitted to participate. Out of the 380 clinical trials currently listed on clinicialtrials.gov, 117 have juvenile participants while 263 cater to elderly individuals."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Multiomic Diagnostics in Youth With Psychosis

Aaron Besterman 2022. "Multiomic Diagnostics in Youth With Psychosis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05457140.