Chronic Antioxidant for Cystic Fibrosis

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Cystic Fibrosis
Chronic Antioxidant - DietarySupplement
Eligibility
Any Age
All Sexes
What conditions do you have?
Select

Study Summary

This trial will explore if oxidative stress contributes to both artery dysfunction and exercise intolerance in CF patients.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

4 Primary · 0 Secondary · Reporting Duration: Baseline, week 4, week 8, and week 12

Hour 2
Acute Change in exercise capacity (VO2 peak)
Week 12
Chronic Change in Flow mediated dilation
Chronic Change in exercise capacity (VO2 peak)
Hour 2
Acute Change in Flow mediated dilation

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Chronic Antioxidant Treatment
1 of 2
Acute Antioxidant Treatment
1 of 2
Experimental Treatment

13 Total Participants · 2 Treatment Groups

Primary Treatment: Chronic Antioxidant · Has Placebo Group · N/A

Chronic Antioxidant Treatment
DietarySupplement
Experimental Group · 1 Intervention: Chronic Antioxidant · Intervention Types: DietarySupplement
Acute Antioxidant TreatmentExperimental Group · 2 Interventions: Acute Antioxidant, Placebo · Intervention Types: DietarySupplement, Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, week 4, week 8, and week 12

Who is running the clinical trial?

Augusta UniversityLead Sponsor
192 Previous Clinical Trials
74,108 Total Patients Enrolled
4 Trials studying Cystic Fibrosis
143 Patients Enrolled for Cystic Fibrosis
Ryan Harris, Ph.D.4.7122 ReviewsPrincipal Investigator - Augusta University
Medical School - University of Kansas, Kansas City, Doctor of Medicine
Augusta University, Medical College of Georgia, Residency in Otolaryngology and Head and Neck Surgery
2 Previous Clinical Trials
339 Total Patients Enrolled
1 Trials studying Cystic Fibrosis
19 Patients Enrolled for Cystic Fibrosis
5Patient Review
He's great and very straightforward.

Eligibility Criteria

Age Any Age · All Participants · 10 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 15th, 2021

Last Reviewed: October 8th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.