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Decision-Making Tasks for Short-Term Memory

N/A

Recruiting

Led By Salman E Qasim, PhD

Research Sponsored by Icahn School of Medicine at Mount Sinai

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up during task participation, approx. 30-45 min in the first 2 weeks of hospital stay

Awards & highlights

Study Summary

This trial aims to uncover how decisions affect memory by combining modeling, brain recordings and epilepsy patient tasks. Results will identify neural mechanisms unifying decision-making and memory.

Who is the study for?

This trial is for individuals with medication-resistant epilepsy who are already set to receive brain monitoring via intracranial EEG or neurostimulation. Participants must be able to follow the study's procedures, provide consent, and speak English or Spanish. Excluded are those with cognitive impairments, unwillingness to undergo electrode implantation, medical risks for surgery/MRI scans, pregnancy, history of psychosis, recent suicide risk, or other significant brain disorders.Check my eligibility

What is being tested?

The study investigates how decision-making affects memory by using computational modeling and direct brain recordings during a dual-task paradigm. Patients undergoing treatment for epilepsy will have their brain activity monitored while they perform tasks designed to probe the interaction between decision-making and memory recall.See study design

What are the potential side effects?

Since this trial involves standard clinical procedures like intracranial EEGs rather than new medications or treatments, side effects relate primarily to potential risks associated with these established neurological assessments and surgeries.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ during task participation, approx. 30-45 min in the first 2 weeks of hospital stay

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~during task participation, approx. 30-45 min in the first 2 weeks of hospital stay

This trial's timeline: 3 weeks for screening, Varies for treatment, and during task participation, approx. 30-45 min in the first 2 weeks of hospital stay for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Firing rate changes

Local-field potentials changes

Secondary outcome measures

Number of hit rates for Memory performance

Number of hit rates for decision-making

Reaction time

Trial Design

1Treatment groups

Experimental Treatment

Group I: Value-manipulationExperimental Treatment1 Intervention

Participants with epilepsy will complete a behavioral task in which they use a laptop computer to do a decision-making and memory task.

Do I qualify?Apply below to find out

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Who is running the clinical trial?

National Institute of Mental Health (NIMH)NIH

2,786 Previous Clinical Trials

2,689,684 Total Patients Enrolled

Icahn School of Medicine at Mount SinaiLead Sponsor

862 Previous Clinical Trials

525,601 Total Patients Enrolled

Salman E Qasim, PhDPrincipal InvestigatorIcahn School of Medicine at Mt. Sinai

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research endeavor accepting participants of sixty years or older?

"This clinical study is open to individuals aged between 18 and 65."

Answered by AI

Is there currently an enrollment period for participants in this experiment?

"This clinical trial is not presently accepting patients, as evidenced by the data hosted on clinicaltrials.gov. The first posting date of this study was October 1st 2023 and it has been recently updated to reflect changes in protocol or recruitment status; however, there are currently one other trials actively recruiting participants for enrollment at this time."

Answered by AI

Is my eligibility to participate in this clinical exploration verified?

"In order to be approved for this research, individuals must possess short-term memory and lie in the 18 to 65 year age range. Approximately 25 participants are being sought after."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

The Computational and Neural Mechanisms Linking Decision-making and Memory in Humans

Salman E Qasim 2023. "The Computational and Neural Mechanisms Linking Decision-making and Memory in Humans". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06072378.