Partner-based Exercise for Cancer Caregivers and Patients

(C4C Trial)

JL
MK
Overseen ByMelanie Keats, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Nova Scotia Health Authority
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores a 12-week exercise program designed for cancer patients and their caregivers. The goal is to determine if exercising together can reduce stress and improve the health of both caregivers and those they care for. The program includes a mix of different exercises (multimodal exercise) performed twice a week. Individuals who have had cancer or are caring for someone with cancer and currently do not exercise much might be suitable candidates. Participants should be capable of light physical activity and must not have any medical conditions that would make exercising unsafe.

As an unphased trial, this study provides a unique opportunity to enhance well-being through exercise without the constraints of a traditional clinical trial phase.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this exercise intervention is safe for cancer caregivers and patients?

Research has shown that a mix of exercises, such as aerobic activities, strength training, and stretching, is generally safe for participants. In a previous study, individuals who engaged in these exercises experienced less fatigue related to cancer treatment, a common concern. This indicates that the exercises helped reduce tiredness and increased energy levels.

Another study focused on a 12-week exercise program for older adults with advanced cancer. The results demonstrated that the program was not only manageable but also beneficial. It improved physical tiredness, quality of life, and even reduced pain and breathing problems.

However, some research indicates that the risks of exercise for cancer patients are not fully understood yet. More studies are needed to explore any possible risks. Overall, participants in these studies managed the exercise programs well, and no major safety issues were found.

In summary, evidence suggests that a combination of exercises is generally well-tolerated and can be helpful for cancer patients and their caregivers.12345

Why are researchers excited about this trial?

Researchers are excited about the partner-based multimodal exercise program because it offers a holistic and supportive approach for both cancer patients and their caregivers, unlike traditional treatments that primarily focus on the patient alone. This intervention encourages physical activity through a 12-week, twice-weekly regimen that combines different exercise types, which can improve physical and emotional well-being for both parties involved. By involving caregivers directly, the program not only aims to boost physical health but also strengthens emotional bonds and mutual support, potentially leading to better adherence and outcomes than standard care.

What evidence suggests that this exercise program might be effective for cancer caregivers and patients?

Research has shown that a mix of exercises, such as aerobic activities, strength training, and stretching, can help ease cancer-related tiredness. One study found that these exercises had a small but real positive effect on reducing fatigue. Another study discovered that exercise programs can improve both physical and mental health in cancer patients, lessen treatment side effects, and shorten hospital stays. Additionally, exercise-based rehabilitation can increase fitness and strength. This trial will test a 12-week, twice-weekly partner-based multimodal exercise program, suggesting that a structured exercise program can benefit cancer patients and their caregivers.26789

Who Is on the Research Team?

MK

Melanie Keats, PhD

Principal Investigator

Dalhousie University / Nova Scotia Health

Are You a Good Fit for This Trial?

This trial is for adult cancer patients at any stage of treatment, including up to 5 years post-treatment, and their caregivers. Caregivers must be providing support but not currently meeting the Canadian guidelines for physical activity (less than 150 minutes of moderate exercise per week). Both parties need to be able to do some low-intensity exercise and consent in English.

Inclusion Criteria

Able to perform discontinuous low intensity physical activity at a minimum
I am a cancer patient or survivor at any stage up to 5 years post-treatment.
Able to provide informed written consent in English
See 2 more

Exclusion Criteria

For informal caregivers: Bereaved caregivers
Patients/survivors and caregivers will be excluded from the study if they have any medical conditions that would contraindicate exercise

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in a 12-week, partner-based exercise intervention including aerobic, resistance, balance, and flexibility exercises

12 weeks
Twice weekly sessions

Follow-up

Participants are monitored for changes in caregiver burden, physical and psychological health, and other health metrics

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Multimodal exercise
Trial Overview The study tests a 12-week partner-based exercise program's feasibility and acceptability. It aims to see if exercising together affects the caregiver's burden as well as both the caregiver’s and patient’s physical and psychological health.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Multimodal Exercise InterventionExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Nova Scotia Health Authority

Lead Sponsor

Trials
302
Recruited
95,300+

Citations

Effects of Supervised Multimodal Exercise Interventions on ...Multimodal interventions including aerobic exercise, resistance training, and stretching improved CRF symptoms (SMD = −0.23; 95% CI: −0.37 to −0.09; P = 0.001).
Multimodal group-based tele-prehabilitation for cancer ...Multimodal prehabilitation can optimize the physical and psychological health of cancer patients, reduce treatment side effects, hospital stay, and accelerate ...
Efficacy of multimodal exercise-based rehabilitation on ...We examined the efficacy of a 12-month exercise-based rehabilitation program on self-reported PA, cardiorespiratory fitness (VO2peak), strength, and patient- ...
Effectiveness of Therapeutic Exercise Models on Cancer ...During chemotherapy, aerobic and/or resistance exercise showed a positive trend compared with flexibility exercise showed a positive trend in reducing cancer- ...
Activating cancer communities through an exercise ...Effectiveness was assessed using fitness and patient reported outcomes as described above. Program retention and costs associated with program ...
Efficacy of multimodal exercise-based rehabilitation on ...A 12-month exercise-based rehabilitation program is an effective strategy to promote PA and improve VO2peak in cancer survivors. Keywords. cancer survivors ...
Harms of exercise training in patients with cancer ...We demonstrate that the harms of exercise, prescribed alone or as part of multimodal interventions, is uncertain in patients with cancer undergoing systemic ...
Effects of a 12-Week Multimodal Exercise Intervention ...The study aim was to investigate the feasibility and effect of a multimodal exercise intervention in older patients with advanced cancer (stages III/IV).
Supervised, structured and individualized exercise in ...Our results indicate that the exercise intervention not only had a positive effect on physical fatigue and HRQOL but also on pain and dyspnea.
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