75 Participants Needed

Inner Speech Training for Developmental Language Disorder

Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: MGH Institute of Health Professions
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

The complex and unclear relationship between language and executive function (EF) creates barriers to developing effective interventions for children with developmental language disorder (DLD) whose language difficulties often co-occur with impaired EF. Children and adults with typical language development (TD) facilitate their EF by using self-directed language, or verbal mediation, to guide conscious reflection and override habitual behaviors. Conversely, children with DLD do not use verbal mediation to support EF efficiently or effectively. Promising evidence suggests that language-based training can shape verbal mediation and improve EF task performance in children with TD, which makes it pertinent to determine whether verbal mediation training benefits children with DLD. Specifically, modeling interventions have been shown to promote learning of language forms without taxing the cognitive resources required for learning such as attention or working memory, which are known to be impaired among children with DLD. The long-term goal of the proposed work is to optimize intervention outcomes for children with DLD by elucidating the complex relationship between language and executive functions. The objective of this project is to determine the impact of modeling verbal mediation on shifting task performance in school-aged children with DLD. Shifting, also known as cognitive flexibility, is the ability to alternate between operations or mental sets. It is an important EF because it is the pivot point between multiple goal-directed tasks when language use is critical for guiding action. Children aged 8-10 years will complete three versions of a shifting task over three phases: pre-intervention, intervention, and post-intervention. During the intervention phase, half of the participants with DLD will be exposed to a task model with verbal mediation (training), while the other half will be exposed to a silent task model (control). The investigators will determine the effect of modeling verbal mediation on the subsequent use of verbal mediation (Aim 1) and behavioral and electrophysiological measures of shifting ability (Aim 2). Indirect measures of shifting (i.e., accuracy and reaction time) will be supplemented with an electrophysiological marker of shifting that reflects real-time cue processing. This combination of methods provides insight to changes in processing following intervention that may precede and predict subsequent changes in behaviors. Our central hypothesis is that modeling verbal mediation will facilitate more effective use of verbal mediation and improve shift cue processing in children with DLD. The project will provide a theoretical framework for the role of language in shaping goal-directed behavior and the first examination of electrophysiological change in shifting following a verbal mediation intervention. Results will have a significant impact on clinical practice by advancing knowledge about a promising language-based intervention to support EF and other goal-directed tasks.

Eligibility Criteria

This trial is for children aged 8 to just under 10 years old with developmental language disorders. They must pass a hearing test, primarily speak English, and have specific scores on the TILLS Identification Core Score indicating language difficulties.

Inclusion Criteria

I passed a hearing test in both ears.
My TILLS score is less than 34.
My TILLS score is 34 or higher.
See 1 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks
1 visit (in-person)

Pre-intervention

Participants complete standardized assessments and initial shifting task

1 visit
1 visit (in-person)

Intervention

Participants undergo verbal mediation training or control condition

1 visit
1 visit (in-person)

Post-intervention

Participants complete post-intervention assessments and shifting task

1 visit
1 visit (in-person)

Follow-up

Participants are monitored for changes in verbal mediation and shifting performance

2-4 weeks

Treatment Details

Interventions

  • Modeling Only
  • Modeling with Verbal Mediation
Trial Overview The study tests two methods of improving executive function in kids with language disorders: one uses modeling with verbal guidance (verbal mediation), and the other uses silent modeling. The impact on cognitive flexibility will be measured behaviorally and through brain activity.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: Training ArmExperimental Treatment1 Intervention
Modeling with Verbal Mediation
Group II: Control ArmActive Control1 Intervention
Modeling Only

Find a Clinic Near You

Who Is Running the Clinical Trial?

MGH Institute of Health Professions

Lead Sponsor

Trials
19
Recruited
2,200+

National Institute on Deafness and Other Communication Disorders (NIDCD)

Collaborator

Trials
377
Recruited
190,000+
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