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Behavioural Intervention

Single-pulse Peak Phase TMS for Behavior

N/A

Recruiting

Research Sponsored by Rutgers, The State University of New Jersey

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up [time frame: day 0 (day of testing)]

Awards & highlights

Study Summary

This trial aims to study how a type of brain stimulation called TMS affects how our brain responds to rewards when we are making decisions. Researchers will use a brain signal called frontal midline theta to see

Who is the study for?

This trial is for individuals struggling with addiction. Participants should be able to perform decision-making tasks and have no conditions that would interfere with TMS treatment or the measurement of brain activity.Check my eligibility

What is being tested?

The study tests if Active single pulse Transcranial Magnetic Stimulation (TMS) to the frontal cortex can influence reward processing in the brain during goal-directed behavior, potentially affecting choices and task performance.See study design

What are the potential side effects?

While not specified here, common side effects of TMS may include headache, scalp discomfort at the site of stimulation, tingling or spasms in facial muscles, lightheadedness, and rare risk of seizure.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ [time frame: day 0 (day of testing)]

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~[time frame: day 0 (day of testing)]

This trial's timeline: 3 weeks for screening, Varies for treatment, and [time frame: day 0 (day of testing)] for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Event-related Brain Oscillation: Frontal Midline Theta

Reward learning

Trial Design

2Treatment groups

Experimental Treatment

Group I: Single-pulse Trough Phase TMSExperimental Treatment1 Intervention

Participants will receive a single active TMS pulse during the trough phase target of each task trial and delivered at 110% of participants' resting motor threshold over the predefined frontal target . For the second TMS session, participants will receive single pulse Sham TMS during the peak phase target of each task trial and delivered at 110% of participants' resting motor threshold over the predefined frontal target. Total number of TMS pulse for each session is 520 pulses

Group II: Single-pulse Peak Phase TMSExperimental Treatment1 Intervention

Participants will receive a single active TMS pulse during the peak phase target of each task trial and delivered at 110% of participants' resting motor threshold over the predefined frontal target . For the second TMS session, participants will receive single pulse Sham TMS during the peak phase target of each task trial and delivered at 110% of participants' resting motor threshold over the predefined frontal target. Total number of TMS pulse for each session is 520 pulses

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Rutgers, The State University of New JerseyLead Sponsor

429 Previous Clinical Trials

64,204 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still available openings for new participants in this research study?

"As per the details available on clinicaltrials.gov, this investigation is presently in the process of seeking suitable participants. Initially shared on February 14th, 2024, it underwent its most recent revision on March 14th, 2024."

Answered by AI

Does this medical study include individuals who are at least 70 years of age in their patient recruitment?

"Individuals between 18 and 55 years old are eligible to participate in this research as per the age requirements."

Answered by AI

What is the upper limit of individuals partaking in this clinical investigation?

"Indeed, information on clinicaltrials.gov indicates that this trial is actively enrolling participants. The study was first posted on February 14th, 2024 and most recently revised on March 14th, 2024. Recruitment aims to include a total of 28 patients from one specified site."

Answered by AI

Do I meet the necessary criteria to be considered as a potential candidate for involvement in this medical study?

"Individuals aged between 18 and 55 years old with a history of substance dependence are eligible for participation in this clinical study, which aims to enroll a total of 28 participants."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Modulating Reward Learning Using Transcranial Magnetic Stimulation

Travis Baker, PhD 2024. "Modulating Reward Learning Using Transcranial Magnetic Stimulation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06323057.

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