Mediterranean Diet for Inflammatory Bowel Disease
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how a Mediterranean diet, rich in fruits, vegetables, and healthy fats, might benefit people with inflammatory bowel disease (IBD). Researchers aim to determine if adopting this diet can reduce inflammation, a common concern for those with IBD. Participants will undergo blood and stool tests to monitor changes in inflammation. This trial suits individuals with mild to moderate Crohn's Disease who have not recently changed their medication and are not on antibiotics. As an unphased trial, it offers a unique opportunity to contribute to understanding dietary impacts on IBD.
Will I have to stop taking my current medications?
The trial does not specify if you must stop taking your current medications, but it requires that you are on a stable dose of medications during the study. If your medication dose has changed recently, you may not be eligible to participate.
What prior data suggests that the Mediterranean Diet is safe for individuals with inflammatory bowel disease?
Research has shown that the Mediterranean diet is generally safe and easy for individuals with inflammatory bowel disease (IBD) to follow. Studies have found that this diet can reduce gut inflammation and improve the quality of life for those with IBD, such as Crohn's disease. Reports of negative side effects from this diet are rare. Overall, the Mediterranean diet is considered a helpful way to manage IBD symptoms, with a strong likelihood of providing benefits without causing harm.12345
Why are researchers excited about this trial?
Unlike the standard treatments for Inflammatory Bowel Disease (IBD), which often include medications like corticosteroids and immunosuppressants, the Mediterranean Diet offers a dietary approach to managing the condition. This diet is rich in fruits, vegetables, whole grains, and healthy fats, which may help reduce inflammation naturally. Researchers are excited because this diet could potentially offer a non-pharmacological option that promotes overall health and well-being, possibly reducing the need for medication and its associated side effects.
What evidence suggests that the Mediterranean Diet might be an effective treatment for inflammatory bowel disease?
Research has shown that the Mediterranean diet, which participants in this trial will follow, benefits gut health and helps reduce inflammation in people with inflammatory bowel disease (IBD). Studies have found that this diet can significantly improve symptom frequency, leading to decreased symptoms. For example, one study found that people who followed this diet experienced a better quality of life and less disease activity. Another study reported that 96% of participants had fewer symptoms and less inflammation. Overall, the Mediterranean diet appears promising for managing IBD.678910
Are You a Good Fit for This Trial?
This trial is for adults over 18 with mild to moderate Crohn's Disease, as indicated by specific disease activity and inflammation markers. Participants must not have started or changed their standard treatment recently, be on stable medication doses, and free from certain infections or antibiotic use.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants follow a Mediterranean Diet for 42 days, with blood and stool samples collected for analysis
Follow-up
Participants are monitored for changes in disease state by measuring markers of inflammation
What Are the Treatments Tested in This Trial?
Interventions
- Mediterranean Diet
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, San Diego
Lead Sponsor