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Carbonated Water for Orthostatic Hypotension

N/A
Recruiting
Led By Victoria E Claydon, PhD
Research Sponsored by Simon Fraser University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 0-50 minutes
Awards & highlights

Study Summary

This trial investigates if carbonated water can help people maintain normal blood pressure when standing, so they don't faint or feel dizzy.

Who is the study for?
This trial is for healthy, English-speaking individuals without a history of cardiovascular or neurological diseases, not pregnant, and who haven't fainted more than once in the past six months. It's designed to see if carbonated water helps people maintain blood pressure when standing up.Check my eligibility
What is being tested?
The study tests whether drinking 500mL of carbonated water improves orthostatic tolerance—the ability to keep blood pressure stable when standing—compared to the same amount of still water. A smaller volume (50mL) of still water serves as an additional control.See study design
What are the potential side effects?
There are no significant side effects expected from consuming carbonated or still water in this trial; however, some individuals might experience mild gastrointestinal discomfort due to gas from the carbonation.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~0-50 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and 0-50 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Orthostatic tolerance

Trial Design

6Treatment groups
Experimental Treatment
Group I: 50mL still water first, then 500mL still water, then 500 mL carbonated waterExperimental Treatment3 Interventions
Participants will undergo this test on three separate days. On each day participants will be asked to drink a glass of water: either a 50mL drink of still water (control condition), a 500mL drink of still (non-carbonated) water, or a 500mL drink of carbonated water. In this arm of the study, participants will receive 50mL still water on the first test day, 500mL carbonated water on the second test day, then 500mL carbonated water on the third day.
Group II: 50mL still water first, then 500mL carbonated water, then 500 mL still waterExperimental Treatment3 Interventions
Participants will undergo this test on three separate days. On each day participants will be asked to drink a glass of water: either a 50mL drink of still water (control condition), a 500mL drink of still (non-carbonated) water, or a 500mL drink of carbonated water. In this arm of the study, participants will receive 50mL still water on the first test day, 500mL still water on the second test day, then 500mL still water on the third day.
Group III: 500mL still water first, then 50mL still water, then 500 mL carbonated waterExperimental Treatment3 Interventions
Participants will undergo this test on three separate days. On each day participants will be asked to drink a glass of water: either a 50mL drink of still water (control condition), a 500mL drink of still (non-carbonated) water, or a 500mL drink of carbonated water. In this arm of the study, participants will receive 500mL still water on the first test day, 50mL still water on the second test day, then 500mL carbonated water on the third day.
Group IV: 500mL still water first, then 500 mL carbonated water, then 50mL still waterExperimental Treatment3 Interventions
Participants will undergo this test on three separate days. On each day participants will be asked to drink a glass of water: either a 50mL drink of still water (control condition), a 500mL drink of still (non-carbonated) water, or a 500mL drink of carbonated water. In this arm of the study, participants will receive 500mL still water on the first test day, 500mL carbonated water on the second test day, then 50mL still water on the third day.
Group V: 500mL carbonated water first, then 50mL of still water, then 500mL of still waterExperimental Treatment3 Interventions
Participants will undergo this test on three separate days. On each day participants will be asked to drink a glass of water: either a 50mL drink of still water (control condition), a 500mL drink of still (non-carbonated) water, or a 500mL drink of carbonated water. In this arm of the study, participants will receive 500mL carbonated water on the first test day, 50mL still water on the second test day, then 500mL still water on the third day.
Group VI: 500mL carbonated water first, then 500mL of still water, then 50mL of still waterExperimental Treatment3 Interventions
Participants will undergo this test on three separate days. On each day participants will be asked to drink a glass of water: either a 50mL drink of still water (control condition), a 500mL drink of still (non-carbonated) water, or a 500mL drink of carbonated water. In this arm of the study, participants will receive 500mL carbonated water on the first test day, 500mL still water on the second test day, then 50mL still water on the third day.

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Who is running the clinical trial?

Simon Fraser UniversityLead Sponsor
51 Previous Clinical Trials
9,197 Total Patients Enrolled
Victoria E Claydon, PhDPrincipal InvestigatorProfessor, Biomedical Physiology and Kinesiology
3 Previous Clinical Trials
63 Total Patients Enrolled

Media Library

Water Carbonation Clinical Trial Eligibility Overview. Trial Name: NCT05621460 — N/A
Orthostatic Hypotension Research Study Groups: 500mL carbonated water first, then 500mL of still water, then 50mL of still water, 50mL still water first, then 500mL still water, then 500 mL carbonated water, 500mL still water first, then 500 mL carbonated water, then 50mL still water, 500mL carbonated water first, then 50mL of still water, then 500mL of still water, 500mL still water first, then 50mL still water, then 500 mL carbonated water, 50mL still water first, then 500mL carbonated water, then 500 mL still water
Orthostatic Hypotension Clinical Trial 2023: Water Carbonation Highlights & Side Effects. Trial Name: NCT05621460 — N/A
Water Carbonation 2023 Treatment Timeline for Medical Study. Trial Name: NCT05621460 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the trial enrollment open to individuals under 65 years of age?

"According to the guidelines of this medical experiment, suitable candidates must be between 19 and 50 years old."

Answered by AI

Would I be eligible to join in this clinical research?

"This research requires 25 individuals aged between 19 and 50 who are currently experiencing orthostatic hypotension. In addition, participants must be in good health and capable of conversation in English."

Answered by AI

Is the recruitment phase of this research endeavor still underway?

"Affirmative. The online records hosted on clinicaltrials.gov indicates that this investigation is currently seeking volunteers, with the trial having been first posted on November 1st 2022 and updated most recently on November 10th 2022. 25 participants are needed for recruitment across a single site."

Answered by AI

How many individuals are currently taking part in this study?

"Affirmative. The information on clinicaltrials.gov indicates that this trial is recruiting participants at present, having been initially posted on November 1st 2022 and last modified on the 10th of November in the same year. A total of 25 patients need to be enrolled from one site."

Answered by AI
~0 spots leftby Apr 2024