Your session is about to expire
← Back to Search
Glycemic Management for High Blood Sugar in Surgical Patients
N/A
Waitlist Available
Research Sponsored by University of Calgary
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Undergoing a surgical procedure, adults (older than 18 years of age), admitted to the hospital for more than 24 hours after their surgical procedure.
Be older than 18 years old
Must not have
Under 18 years of age
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 weeks after the index surgical procedure
Awards & highlights
No Placebo-Only Group
Summary
This trial tests a special care plan called PGMP to manage blood sugar in surgical patients at risk of high levels. It aims to improve recovery by monitoring and controlling blood sugar, reducing complications, and shortening hospital stays.
Who is the study for?
This trial is for adults over 18 who are undergoing surgery and will be in the hospital for more than a day afterward. It's designed to help those at risk of high blood sugar after their operation, including people with known or undiagnosed diabetes.
What is being tested?
The trial tests a Perioperative Glycemic Management Pathway (PGMP) against usual care to see if it can better manage post-surgery blood sugar levels, shorten hospital stays, reduce readmissions, and save costs. The study involves multiple hospitals and uses a stepped-wedge design.
What are the potential side effects?
Since this intervention focuses on managing blood sugar levels around the time of surgery rather than medication side effects per se, specific side effects aren't listed but may include risks associated with any changes in glycemic control.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am an adult who will be in the hospital for more than a day after surgery.
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I am under 18 years old.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 365 days after surgery
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~365 days after surgery
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Length of stay
Secondary study objectives
Hypoglycemia
Readmissions
Other study objectives
Surgical site infections
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
2Treatment groups
Active Control
Group I: Intervention: PGMPActive Control1 Intervention
Sites will implement a perioperative glycemic management pathway based on national guidelines and current evidence, with support of an implementation scientist team.
Group II: Non-intervention: usual careActive Control1 Intervention
Sites will perform usual perioperative glycemic management.
Research Highlights
Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.Mechanism Of Action
Side Effect Profile
Prior Approvals
Other Research
Common treatments for high blood sugar include insulin therapy and GLP-1 receptor agonists. Insulin therapy lowers blood glucose by promoting cellular glucose uptake and reducing hepatic glucose production.
GLP-1 receptor agonists enhance meal-induced insulin secretion, inhibit glucagon release, and slow gastric emptying. These mechanisms are vital for high blood sugar patients, particularly in perioperative settings, to prevent complications like infections, extended hospital stays, and increased mortality.
Protocol for a prospective, international cohort study on the Management and Outcomes of Perioperative Care among European Diabetic Patients (MOPED).Diabetes and cardiovascular disease: from new mechanisms to new therapies.Perioperative Glycemic Management of Patients Undergoing Bariatric Surgery.
Protocol for a prospective, international cohort study on the Management and Outcomes of Perioperative Care among European Diabetic Patients (MOPED).Diabetes and cardiovascular disease: from new mechanisms to new therapies.Perioperative Glycemic Management of Patients Undergoing Bariatric Surgery.
Find a Location
Who is running the clinical trial?
University of CalgaryLead Sponsor
809 Previous Clinical Trials
876,814 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I am under 18 years old.I am an adult who will be in the hospital for more than a day after surgery.
Research Study Groups:
This trial has the following groups:- Group 1: Intervention: PGMP
- Group 2: Non-intervention: usual care
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Share this study with friends
Copy Link
Messenger