Music Therapy for Glioblastoma

(MELODY Trial)

PI
Overseen ByPrincipal Investigator, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Must be taking: Temozolomide
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The Brain Cancer Program, in partnership with the Center for Music and Medicine at Johns Hopkins, will study whether music therapy is feasible in newly diagnosed GBM patients undergoing standard care.

Who Is on the Research Team?

MH

Matthias Holdhoff, MD

Principal Investigator

Johns Hopkins -Sidney Kimmel Cancer Center

GT

Grace Tobin, MD

Principal Investigator

Johns Hopkins University

Are You a Good Fit for This Trial?

This trial is for individuals with newly diagnosed Glioblastoma who can use a computer, access the web, attend virtual music therapy sessions, understand and respond to surveys in English, and hear music properly. It's not suitable for those who lack these capabilities.

Inclusion Criteria

I have been diagnosed with glioblastoma.
I can understand and answer survey questions.
I have a computer and internet access.
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive music therapy sessions twice a week for 8 weeks, either with or without a music therapist, and complete quality of life surveys weekly.

8 weeks
16 virtual sessions (via Zoom)

Follow-up

Participants are monitored for safety and effectiveness after treatment

6 months

Long-term follow-up

Participants' survey completion rates are monitored over a longer period

2 years

What Are the Treatments Tested in This Trial?

Interventions

  • Music Intervention

Trial Overview

The study explores the feasibility of using music therapy as part of standard care for patients with Glioblastoma. Participants will engage in virtual music therapy sessions organized by Johns Hopkins' Brain Cancer Program and Center for Music and Medicine.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Arm B- without Music TherapistsExperimental Treatment1 Intervention
Group II: Arm A- with Music TherapistsExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Lead Sponsor

Trials
578
Recruited
33,600+

Keep Punching Foundation

Collaborator

Trials
2
Recruited
60+