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HEPA Filter

Air Purification for Eosinophilic COPD

Q: Are individuals being accepted into this research study at the present moment?

<p>Clinicaltrials.gov reveals that this medical trial is no longer enrolling participants, as the post was first created on March 15th 2021 and last edited November 3rd 2022. Nonetheless, there are still 279 other studies seeking candidates for their clinical trials.</p>

N/A

Waitlist Available

Led By Mary B Rice, MD MPH

Research Sponsored by Beth Israel Deaconess Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Physician diagnosis of COPD [Global Initiative for Obstructive Lung Disease (GOLD) Stage II-IV disease with Forced Expiratory Volume (FEV1)/ Forced Vital Capacity (FVC) ≤70% and FEV1 (% predicted) <80%]

Age of 40 years or more

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline [3 months before intervention and day of intervention] and post intervention [7 days, 6 months and 12 months]

Awards & highlights

Study Summary

This trial will study whether air purifiers help improve the lung health of people with COPD who have eosinophils in their airways.

Who is the study for?

Adults over 40 with eosinophilic COPD, a history of smoking (at least 10 pack-years), and specific lung function test results can join. They must not already use HEPA air purifiers, live in long-term care, plan to move soon, or have severe diseases with less than 2 years life expectancy.Check my eligibility

What is being tested?

The trial is testing if home air purifiers improve lung health in people with eosinophilic COPD. Participants are randomly divided into two groups: one gets real HEPA filter air purifiers and the other gets fake ones.See study design

What are the potential side effects?

Since this trial involves using an air purifier versus a sham device, there are no direct medical side effects expected from the interventions themselves.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have been diagnosed with moderate to severe COPD.

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I am 40 years old or older.

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I have smoked the equivalent of 10 or more packs of cigarettes per year.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline [3 months before intervention and day of intervention] and post intervention [7 days, 6 months and 12 months]

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline [3 months before intervention and day of intervention] and post intervention [7 days, 6 months and 12 months]

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline [3 months before intervention and day of intervention] and post intervention [7 days, 6 months and 12 months] for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in forced expiratory volume in 1 second (FEV1)

Secondary outcome measures

Change in functional capacity by 6 minute walk test

Change in health status (also called health-related quality of life) by St. George Respiratory Questionnaire

Change in respiratory symptoms

Other outcome measures

Change in nasal inflammatory mediators

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: True air purifierExperimental Treatment1 Intervention

Participants will receive a HEPA air purifier in the bedroom and living room.

Group II: Sham air purifierPlacebo Group1 Intervention

Participants will receive a sham air purifier that will be installed in the bedroom and living room. These purifiers will make a noise, but will not filter the air.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Air purifier

2017

N/A

~190

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

Beth Israel Deaconess Medical CenterLead Sponsor

836 Previous Clinical Trials

13,010,176 Total Patients Enrolled

National Institute of Environmental Health Sciences (NIEHS)NIH

284 Previous Clinical Trials

1,232,577 Total Patients Enrolled

Mary B Rice, MD MPHPrincipal InvestigatorBeth Israel Deaconess Medical Center

Media Library

Air Purifier (HEPA Filter) Clinical Trial Eligibility Overview. Trial Name: NCT04252235 — N/A

Chronic Obstructive Pulmonary Disease Research Study Groups: Sham air purifier, True air purifier

Chronic Obstructive Pulmonary Disease Clinical Trial 2023: Air Purifier Highlights & Side Effects. Trial Name: NCT04252235 — N/A

Air Purifier (HEPA Filter) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04252235 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are individuals being accepted into this research study at the present moment?

"Clinicaltrials.gov reveals that this medical trial is no longer enrolling participants, as the post was first created on March 15th 2021 and last edited November 3rd 2022. Nonetheless, there are still 279 other studies seeking candidates for their clinical trials."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Home Air Purification for Eosinophilic COPD

Mary Rice 2021. "Home Air Purification for Eosinophilic COPD". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04252235.

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