Almonds for Wrinkles

Overseen By Sarah Adnan

Age: 18+

Sex: Female

Trial Phase: Academic

Sponsor: Integrative Skin Science and Research

Disqualifiers: Nut allergy, Pregnant, Autoimmune, others

Approved in 1 Jurisdiction This treatment is already approved in other countries

Compensation: Varies

Number of Visits: Unknown

Duration: 24 weeks

60 Participants Needed

Trial Summary

What is the purpose of this trial?

Investigate the effects of almond consumption on collagen production, elastin levels, wrinkles, and pigmentation among premenopausal women and postmenopausal women belonging to all Fitzpatrick skin types.

Research Team

Raja Sivamani, MD MS AP

Principal Investigator

Integrative Skin Science and Research

Eligibility Criteria

This trial is for premenopausal and postmenopausal women aged 35-70, with a BMI of 18.5-35 kg/m2, who have maintained their diet and skincare routine for at least 1 month. It's not suitable for those with nut allergies, on oral collagen or vitamin E supplements, pregnant/breastfeeding women, recent facial procedure recipients, tobacco users, or individuals with certain skin diseases.

Inclusion Criteria

You have been following the same diet for the past 6 months and will continue to do so during the study.

I am a postmenopausal woman, having not had a period for over a year.

I am between 35 and 70 years old.

Exclusion Criteria

Individuals who are unwilling to discontinue vitamin E or nut containing supplements 2 weeks prior to and during the intervention

I am willing to stop taking oral collagen supplements 1 month before the study starts.

I have a condition that affects my skin's reaction to sunlight or causes weak collagen.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants consume almonds or a placebo snack 5 times per week

24 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Treatment Details

Interventions

• Almond

Trial Overview The study examines if eating whole almonds affects the production of collagen in the skin and improves wrinkles and pigmentation among women of all Fitzpatrick skin types. Participants will be compared to those consuming a non-nut snack to see differences in skin health outcomes.

Participant Groups

Group I: Almonds Experimental Treatment 1 Intervention

Consumption of almonds 5 times per week

Group II: Control Snack Placebo Group 1 Intervention

Consumption of protein and calorie matched non-nut-based food 5 times per week

Who Is Running the Clinical Trial?

Integrative Skin Science and Research

Lead Sponsor

Trials

33

Recruited

2,000+