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Negative Affect Task for Binge Eating Disorder
N/A
Recruiting
Led By Guido KW Frank, MD
Research Sponsored by University of California, San Diego
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Binge Eating Disorder: Age 18-55 years old, Edinburgh Handedness Inventory Revised (EHI-R) LQ* score > +200, DSM 5 diagnosis of Binge Eating Disorder with specific criteria
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 5 years
Awards & highlights
Study Summary
This trial is studying how well brain imaging works in people with binge eating disorder or bulimia nervosa.
Who is the study for?
Adults aged 18-55 with obesity (BMI > 30 kg/m2) and diagnosed with Bulimia Nervosa or Binge Eating Disorder, experiencing marked distress from binge eating. Participants should have a stable weight and food intake for the past month, no major medical illnesses, no history of substance abuse or certain psychiatric disorders, not pregnant or breastfeeding, and without metal implants.Check my eligibility
What is being tested?
The trial is studying how negative emotions affect people with bulimia nervosa and binge eating disorder. It aims to link these feelings to brain function related to reward learning, food value computation, cognitive control circuits, and whether this can predict future eating behavior.See study design
What are the potential side effects?
Since this study focuses on behavioral tasks rather than medication or invasive procedures, significant side effects are not expected. However, participants may experience emotional discomfort when discussing their eating habits or during assessments.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am 18-55 years old with Binge Eating Disorder and right-handed as per the EHI-R.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 5 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~5 years
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Brain Activation and Food Intake/negative Affect Relationships
Food Choice Brain Response to Negative Affect fMRI Task
Taste Reward Brain Response to Negative Affect fMRI Task
Trial Design
1Treatment groups
Experimental Treatment
Group I: BehavioralExperimental Treatment1 Intervention
Negative Affect Task
Find a Location
Who is running the clinical trial?
University of California, San DiegoLead Sponsor
1,121 Previous Clinical Trials
1,520,514 Total Patients Enrolled
Sanford ResearchOTHER
5 Previous Clinical Trials
731 Total Patients Enrolled
University of Colorado, DenverOTHER
1,738 Previous Clinical Trials
2,149,116 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- You have a condition called binge eating disorder, where you frequently eat large amounts of food in a short period of time.You eat really fast, much faster than usual.You often eat a lot of food even when you're not actually hungry.My weight has been within 10% of my average since puberty.I am considered medically obese.I have been obese for at least one year.I am 18-55, with a BMI over 30, stable diet for 4 weeks, right-handed as per EHI-R, and have been obese for at least a year.You feel like you can't control your eating during certain episodes.Your thoughts about your body shape and weight have a big impact on how you see yourself.You eat so much that you feel very uncomfortable afterwards.Your Edinburgh Handedness Inventory Revised (EHI-R) LQ* score is higher than +200.You have a diagnosis of Bulimia Nervosa, which means you often eat large amounts of food in a short time period, more than most people would eat in the same situation.I am not pregnant, breastfeeding, on certain medications, have a psychiatric disorder, a major illness, substance abuse history, or metal implants.I am 18-55 years old with Binge Eating Disorder and right-handed as per the EHI-R.I am between 18 and 55 years old.You feel really bad, sad, or guilty after eating too much.People who are in good health and do not have any medical conditions.You have a condition called bulimia nervosa, which involves binge eating and purging.Your body mass index (BMI) is greater than 30 kg/m2.You regularly engage in unhealthy behaviors to avoid gaining weight, like making yourself throw up, using too many laxatives or diuretics, not eating for long periods, or exercising excessively.You have a diagnosis of Binge Eating Disorder, which means you frequently have episodes of eating large amounts of food in a short period of time.I am 18-55, have a healthy weight, regular menstrual cycles (if applicable), and am right-handed.You feel very upset and distressed about your binge eating.Your binge eating episodes are not followed by attempts to "make up" for it, like purging or excessive exercise.You feel embarrassed eating by yourself.You have been following a consistent eating schedule for the past 4 weeks.
Research Study Groups:
This trial has the following groups:- Group 1: Behavioral
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Does this research program accept geriatric participants?
"In order to be eligible for this study, the participant must not exceed 55 years of age and should have at least attained the age of majority."
Answered by AI
What is the current participant population of this trial?
"Absolutely, the clinicaltrials.gov website confirms that recruitment for this medical trial is underway. Originally posted on February 1st 2018 and last updated September 28th 2022, 410 patients are being sought after across one location."
Answered by AI
Are there any open spots left in this experiment?
"Affirmative. Evidenced by its presence on clinicaltrials.gov, this study is recruiting participants at present. Officially announced on February 1st 2018, the trial was last updated on September 28th 2022 and seeks to include 410 patients from a single site."
Answered by AI
Does this trial accept volunteers?
"To qualify for this trial, individuals must possess obesity and fall within the 18-55 age range. Approximately 410 people are being sought as participants in this study."
Answered by AI
Who else is applying?
What state do they live in?
California
How old are they?
18 - 65
What site did they apply to?
University of California at San Diego
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
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