Light Therapy for Depression
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new light therapy for individuals experiencing a major depressive episode. Participants will use a wearable headset at home, receiving either real or sham light therapy (60Hz Intermittent Light Therapy or Sham Light Therapy) for 30 minutes each day, from Monday to Friday, over three weeks. The trial aims to determine if the light therapy is safe and effective in reducing depression symptoms. This study may suit adults diagnosed with major depressive disorder who are on a stable dose of antidepressant medication. As an unphased trial, it offers participants the chance to contribute to innovative research that could lead to new treatment options for depression.
Do I need to stop my current medications to join the trial?
The trial does not specify that you need to stop your current medications. However, you must be on a stable dose of antidepressant medication for at least 30 days before joining.
What prior data suggests that this light therapy is safe for treating depression?
Research has shown that 60Hz intermittent light therapy is under study for its safety and effectiveness in treating depression. Earlier studies found that participants generally tolerated this type of light therapy well, with no major side effects reported.
The therapy involves a wearable headset that flashes light in short bursts. Early findings indicate only mild side effects, such as slight eye strain or headaches, which are common with light-based treatments. These effects are usually temporary and resolve on their own.
Ongoing research aims to confirm the safety of this light therapy for individuals with major depression. While more data is needed, early results appear promising for those considering participation in such trials.12345Why are researchers excited about this trial?
Researchers are excited about 60Hz Intermittent Light Therapy for depression because it offers a non-invasive alternative to traditional treatments like antidepressant medications and psychotherapy. Unlike these options, this light therapy uses specific frequencies of light delivered in the comfort of a patient's home, potentially making it more accessible and convenient. Additionally, while most antidepressants can take weeks to show effectiveness, light therapy has the potential to deliver noticeable improvements more quickly, which is particularly promising for those seeking faster relief from depressive symptoms.
What evidence suggests that 60Hz intermittent light therapy is effective for depression?
Research shows that 60Hz intermittent light therapy, which participants in this trial may receive, might help treat depression. Studies have found that this light therapy is safe and well-tolerated by people with major depressive disorder. Animal studies suggest it could also improve mood. Additionally, a study where participants knew they were receiving the therapy found it to be a safe way to manage depression symptoms. While more research is needed to confirm its effectiveness, early results are promising.13678
Who Is on the Research Team?
Giuseppina Pilloni, PhD
Principal Investigator
NYU Langone Health
Are You a Good Fit for This Trial?
Adults with Major Depressive Disorder (MDD) experiencing a major depressive episode can join this study. They'll use a light therapy headset at home for three weeks. People who have other mental health disorders, eye diseases sensitive to light, or are taking medications affecting light sensitivity cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either active or sham 60Hz intermittent light stimulation for 30 minutes daily, five days per week, over three weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- 60Hz Intermittent Light Therapy
- Sham Light Therapy
Find a Clinic Near You
Who Is Running the Clinical Trial?
NYU Langone Health
Lead Sponsor
Syntropic Medical
Collaborator