IMAGINE for Perinatal Depression
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you need to stop your current medications. However, if you are receiving other mental healthcare services, you must have been on a stable treatment regimen for at least 6 months.
What data supports the effectiveness of the treatment IMAGINE for perinatal depression?
Is the treatment in the IMAGINE trial for perinatal depression safe for humans?
The research articles do not provide specific safety data for the treatment in the IMAGINE trial. However, they discuss the general use of antidepressants during pregnancy, noting that while no medication is entirely risk-free, many antidepressants, especially SSRIs (a type of antidepressant), are considered safer than leaving depression untreated during pregnancy.678910
How is the IMAGINE treatment for perinatal depression different from other treatments?
What is the purpose of this trial?
The goal of this clinical trial is to evaluate if a digital group intervention (named IMAGINE) can prevent depression in perinatal populations. The main questions it aims to answer are:Does IMAGINE engage cognitive behavioral therapy targets? Does IMAGINE lead to lower depression scores? Is IMAGINE acceptable, appropriate, usable and feasible?Participants will be randomized to either participate in an IMAGINE group for 12 weeks or receive standard of care. Participants will respond to questionnaires at enrollment and study visits at 12 and 24 weeks after enrollment.
Research Team
Keshet Ronen, PhD, MPH
Principal Investigator
University of Washington
Eligibility Criteria
This trial is for pregnant or postpartum individuals (up to 6 months after birth), aged 16+, at risk of perinatal depression but not currently experiencing major depression. Participants must speak English or Spanish, have stable mental healthcare if any, and access to a smartphone with data.Inclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants are randomized to either participate in the IMAGINE group for 12 weeks or receive standard of care.
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- IMAGINE
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Washington
Lead Sponsor
Seattle Children's Hospital
Collaborator
National Institute of Mental Health (NIMH)
Collaborator
Northwestern University
Collaborator
Brown University
Collaborator
Seattle Children's Research Institute
Collaborator
National Institutes of Health (NIH)
Collaborator