← Back to Search

Behavioral Intervention

Approach Avoidance Training for Alcohol Use Disorder

N/A

Recruiting

Led By Jessica A Bomyea, PhD

Research Sponsored by VA Office of Research and Development

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, post (week 6), follow up 1 (3 mo.), followup 2 (6 mo.)

Awards & highlights

Study Summary

This trial will test a new treatment for alcohol use disorders to see if it helps reduce hazardous drinking and improve social, occupational, and domestic functioning.

Who is the study for?

This trial is for English-speaking Veterans with Alcohol Use Disorder (AUD) who have been sober for no more than 90 days and are stable on any psychotropic medications for at least 4 weeks. It's not suitable for those with a history of severe mental health disorders, neurological conditions, sensory deficits, recent suicidal or homicidal thoughts, or anyone receiving concurrent psychotherapy outside standard care.Check my eligibility

What is being tested?

The study tests Approach Avoidance Training (AAT), a computer-based treatment aiming to alter the impulse to seek out alcohol-related cues. This is combined with standard VA care to see if it helps reduce drinking and improve social and occupational functioning in Veterans with AUD.See study design

What are the potential side effects?

Since AAT involves psychological training rather than medication, typical drug side effects aren't expected. However, participants may experience stress or discomfort from confronting alcohol-related cues during the training.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, post (week 6), follow up 1 (3 mo.), followup 2 (6 mo.)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, post (week 6), follow up 1 (3 mo.), followup 2 (6 mo.)

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, post (week 6), follow up 1 (3 mo.), followup 2 (6 mo.) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in the Drinker Inventory of Consequences (DrInC)

Secondary outcome measures

Change in Alcohol Approach Avoidance Behavioral Assessment (approach bias score)

Change in Alcohol Approach Avoidance Imaging Assessment (BOLD neural signal)

Change in the Timeline Follow-back Procedure (TLFB)

Other outcome measures

Change in Alcohol Cue Reactivity fMRI task

Change in Alcohol Inhibition fMRI task (BOLD neural signal)

Change in Sheehan Disability Scale (SDS)

+2 more

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Approach Avoidance TrainingExperimental Treatment1 Intervention

AAT condition, participants use a joystick to respond to the color of the border surrounding the stimulus images presented (i.e., "pull for green, push for blue"). The stimuli used are alcohol-related images and neutral beverage images. To experimentally manipulate automatic action tendencies, a contingency is set between alcohol stimuli and avoidance behaviors

Group II: Sham TrainingPlacebo Group1 Intervention

In the Sham participants use a joystick to respond to the color of the border surrounding stimulus images presented. There is no contingency between instruction type and pictures (i.e., non-training version of the task)

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Approach Avoidance Training

2015

N/A

~60

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor

1,610 Previous Clinical Trials

3,305,008 Total Patients Enrolled

41 Trials studying Alcoholism

6,163 Patients Enrolled for Alcoholism

Jessica A Bomyea, PhDPrincipal InvestigatorVA San Diego Healthcare System, San Diego, CA

1 Previous Clinical Trials

130 Total Patients Enrolled

Media Library

Approach Avoidance Training (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05372029 — N/A

Alcoholism Research Study Groups: Approach Avoidance Training, Sham Training

Alcoholism Clinical Trial 2023: Approach Avoidance Training Highlights & Side Effects. Trial Name: NCT05372029 — N/A

Approach Avoidance Training (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05372029 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment open to those over the age of eighty-five for this trial?

"This clinical trial has a patient recruitment range of 18 to 65, as specified by the inclusion criteria."

Answered by AI

What are the criteria for eligibility in this medical experiment?

"In order to be admitted into this medical experiment, individuals must demonstrate a history of alcohol consumption and fit within the age brackets of 18-65. The total amount of participants sought is 176."

Answered by AI

Are there any slots still available for individuals to participate in this clinical trial?

"As per the information provided by clinicaltrials.gov, this particular trial is not enrolling any new patients at present. Initially posted on April 3rd 2023 and last updated in May 9th 2022, it has concluded its recruitment phase; however there are 364 other trials that remain open to participants."

Answered by AI