No PEM for COVID-19

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA
COVID-19+1 More
Virtual vs On Site Pulmonary Rehabilitation - Other
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

The purpose of the study is to assess the physiologic, immunologic, and mental health effects of a rehabilitation program on patients with Long Haul COVID (LHC).

Eligible Conditions

  • COVID-19
  • Long Haul COVID or Post Acute Sequella of COVID - PASC (U09.9)

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 8 Secondary · Reporting Duration: 10 weeks

10 weeks
Change in Anxiety scores
Change in Depression scores
Change in General Quality of Life
Change in Sleep Quality Index
Change in a Dyspnea score.
Change in a Fatigue Score
Change in a Post Exertional Malaise score.
Change in aerobic capacity (Peak Oxygen Uptake, Anaerobic Threshold and Maximum Work rate) at 10 weeks after a comprehensive (normal intensity) pulmonary rehabilitation program.
Change in the Inflammatory Cytokines .

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

+ PEM
1 of 2
No PEM
1 of 2
Active Control
Experimental Treatment

40 Total Participants · 2 Treatment Groups

Primary Treatment: No PEM · No Placebo Group · N/A

No PEM
Other
Experimental Group · 1 Intervention: Virtual vs On Site Pulmonary Rehabilitation · Intervention Types: Other
+ PEM
Other
ActiveComparator Group · 1 Intervention: Virtual vs On Site Pulmonary Rehabilitation · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 10 weeks

Trial Background

William Stringer, MD
Principal Investigator
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Closest Location: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center · Torrance, CA
2019First Recorded Clinical Trial
3 TrialsResearching COVID-19
4 CompletedClinical Trials

Eligibility Criteria

Age 18+ · All Participants · 5 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have been exposed to a patient with COVID-19 who has been in a long-haul flight.
You are able to perform a cardiopulmonary exercise test.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.