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Exposure and Response Prevention for Obsessive-Compulsive Disorder

N/A
Recruiting
Led By Amy Rapp, PhD
Research Sponsored by Columbia University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up one-time study visit
Awards & highlights

Study Summary

This trial will test if individuals with OCD and healthy controls differ in their learning strategies, and if those differences are related to changes in neural events.

Who is the study for?
This trial is for English-speaking adults aged 18-50 with a primary diagnosis of OCD of at least moderate severity. It's not suitable for those with significant medical conditions, substance use disorders in the past year, recent Ex/RP therapy for OCD, current psychotropic medication use, or other psychiatric disorders.Check my eligibility
What is being tested?
The study examines how individuals with OCD and healthy controls employ learning strategies differently. It involves one experimental task to collect behavioral data and EEG recordings from each group (30 participants each), using computational modeling to link neural measures to behavior.See study design
What are the potential side effects?
Since this trial involves non-invasive procedures like EEG recording and psychological tasks rather than medications, side effects are minimal but may include discomfort or fatigue during testing.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~one-time study visit
This trial's timeline: 3 weeks for screening, Varies for treatment, and one-time study visit for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Neural Activity

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Behavioral TreatmentExperimental Treatment1 Intervention
Participants diagnosed with OCD will receive 16 sessions (1 hour long) of exposure and response prevention (Ex/RP) delivered twice weekly over the course of eight weeks.
Group II: No interventionActive Control1 Intervention
Healthy controls will not receive treatment over the course of eight weeks.

Find a Location

Who is running the clinical trial?

Columbia UniversityLead Sponsor
1,431 Previous Clinical Trials
2,460,771 Total Patients Enrolled
5 Trials studying Obsessive-Compulsive Disorder
516 Patients Enrolled for Obsessive-Compulsive Disorder
New York State Psychiatric InstituteLead Sponsor
475 Previous Clinical Trials
153,847 Total Patients Enrolled
24 Trials studying Obsessive-Compulsive Disorder
887 Patients Enrolled for Obsessive-Compulsive Disorder
International OCD FoundationUNKNOWN
2 Previous Clinical Trials
114 Total Patients Enrolled
1 Trials studying Obsessive-Compulsive Disorder
58 Patients Enrolled for Obsessive-Compulsive Disorder

Media Library

Exposure and Response Prevention (Ex/RP) Clinical Trial Eligibility Overview. Trial Name: NCT05195476 — N/A
Obsessive-Compulsive Disorder Clinical Trial 2023: Exposure and Response Prevention (Ex/RP) Highlights & Side Effects. Trial Name: NCT05195476 — N/A
Exposure and Response Prevention (Ex/RP) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05195476 — N/A
Obsessive-Compulsive Disorder Patient Testimony for trial: Trial Name: NCT05195476 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are new participants being accepted for this research initiative presently?

"The data posted on clinicaltrials.gov reveals that the trial is currently in its recruitment phase, having first been established back on December 17th 2021 and refreshed most recently on January 4th 2022."

Answered by AI

Is this trial recruiting individuals under the age of 25?

"According to the inclusion criteria, this trial is open for those aged 18-50. There are 23 trials available for minors and 67 for patients over 65 years of age respectively."

Answered by AI

How many participants are engaged in this medical trial?

"Correct. Per the information found on clinicaltrials.gov, this research is actively enrolling candidates who meet its criteria. The trial was initially created on December 17th 2021 and last updated four weeks later on January 4th 2022. They are looking to include 60 patients at a single medical centre."

Answered by AI

What criteria are beneficial for potential participants in this trial?

"To be considered for this clinical trial opportunity, individuals must have a diagnosis of obsessive-compulsive disorder and fall between the ages of 18 to 50. This research is currently looking for approximately 60 participants."

Answered by AI

Who else is applying?

What state do they live in?
North Carolina
New York
How old are they?
18 - 65
What site did they apply to?
New York State Psychiatric Institute
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria

Why did patients apply to this trial?

I've struggled with overcoming trichotillomania for 5 years now resulting in me keeping my hair short despite not wanting to.
PatientReceived no prior treatments

How responsive is this trial?

Typically responds via
Email
Recent research and studies
clinicaltrials.govStudy
Neural Correlates of Compulsivity
Amy Rapp 2021. "Neural Correlates of Compulsivity". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05195476.
~18 spots leftby Apr 2025
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