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Corticosteroid

TDCS for Epilepsy

N/A

Waitlist Available

Led By Anli Liu, MD

Research Sponsored by NYU Langone Health

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Placement of intracranial electrode arrays (grid, strip and or depth electrodes) for seizure focus localization and/or mapping of eloquent cortex

Age ≥ 18 years

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 24 hour post op

Awards & highlights

Study Summary

This trial is measuring the electrical fields caused by tDCS in people with implanted electrodes as part of their evaluation for epilepsy surgery, in order to improve mathematical models. The models can then be used to target tDCS to specific brain regions in healthy and sick people. The stimulations used in this trial are not expected to produce any changes in brain function.

Who is the study for?

This trial is for adults over 18 who can consent and speak English, undergoing evaluation for epilepsy surgery with intracranial electrodes already in place. It's not for those with cognitive impairment, skin issues on the face or forehead, MRI contraindications, adhesive allergies, certain brain pathologies, or recent seizures.Check my eligibility

What is being tested?

The study tests how electrical fields from Transcranial Direct Current Stimulation (TDCS) spread in the brain using measurements from patients' implanted electrodes. This data will help improve models to target TDCS therapy more effectively in future treatments.See study design

What are the potential side effects?

While this study uses low-intensity stimulation that's unlikely to change brain function and is considered safe based on animal studies and clinical trials standards, potential side effects are not detailed here.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have had electrodes placed in my brain to locate seizure sources or map critical brain areas.

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I am 18 years old or older.

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I speak English.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 24 hour post op

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~24 hour post op

This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 hour post op for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Current Intensity

Total charge (stimulation intensity x duration of stimulation in coulombs

Total electrode charge density (total charge/electrode area in coloumbs/meters2) as measured at various subdural and depth electrode recording sites

Trial Design

1Treatment groups

Experimental Treatment

Group I: Direct Cortical MeasurementExperimental Treatment1 Intervention

Consented subjects will also have transcranial electrodes applied at four extracranial sites, below the sterile dressing and distant from the surgical skull defect. The four electrodes will be placed in uniform positions based on the standard 10-10 electrode system, at the temples bilaterally (positions F9 and F10) and at the occiput bilaterally (positions PO9 and PO10). Subjects will be stimulated according to a predetermined set of parameters which fall well within empirically and computationally determined safety thresholds, as discussed above. The entire stimulation protocol is described in detail in section 5, and is anticipated to last no longer than 30 minutes.

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

NYU Langone HealthLead Sponsor

1,367 Previous Clinical Trials

839,711 Total Patients Enrolled

25 Trials studying Epilepsy

3,033 Patients Enrolled for Epilepsy

Anli Liu, MDPrincipal InvestigatorNYU Langone Health

4 Previous Clinical Trials

3 Total Patients Enrolled

4 Trials studying Epilepsy

3 Patients Enrolled for Epilepsy

Media Library

Transcranial Direct Current Stimulation (TDCS) (Corticosteroid) Clinical Trial Eligibility Overview. Trial Name: NCT02263274 — N/A

Epilepsy Research Study Groups: Direct Cortical Measurement

Epilepsy Clinical Trial 2023: Transcranial Direct Current Stimulation (TDCS) Highlights & Side Effects. Trial Name: NCT02263274 — N/A

Transcranial Direct Current Stimulation (TDCS) (Corticosteroid) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02263274 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there opportunities for individuals to become involved in this research at the present time?

"According to clinicaltrials.gov, this research project is no longer accepting participants; the initial post was published on November 1st 2013 and updates ceased on August 4th 2022. Although not presently enrolling patients, 239 other trials are open for recruitment at present."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Direct Cortical Measurement of the Intensity and Pattern of Current Flow Produced by TDCS

2013. "Direct Cortical Measurement of the Intensity and Pattern of Current Flow Produced by TDCS". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02263274.

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