124 Participants Needed

Online Gameplay for Mild Cognitive Impairment

KV
Overseen ByKayci Vickers, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Emory University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether playing games online (Online Gameplay Intervention) can reduce loneliness and increase social connection, particularly for individuals with mild cognitive impairment (MCI), a condition affecting memory and thinking skills. Participants will either begin the game-based program immediately or after a 12-week waiting period. Suitable candidates should live independently, have MCI diagnosed by a healthcare professional, and not experience cognitive issues from other conditions like a stroke. As an unphased trial, this study provides a unique opportunity to contribute to innovative research that could enhance social connections for those with MCI.

Will I have to stop taking my current medications?

Yes, you will need to stop taking any current psychoactive medications to participate in this trial.

What prior data suggests that this online gameplay intervention is safe for adults with mild cognitive impairment?

Research has shown that playing online games is generally safe for people with mild cognitive impairment (MCI). Studies have found that these games can improve thinking skills and daily activities in older adults and may also reduce feelings of depression. Participants in these studies reported no major safety issues.

One study examined esports for people with dementia and MCI and found no serious problems related to playing these games. However, more research is needed to fully understand their benefits.

Overall, participants have well-received playing online games. It appears to be a safe and enjoyable way to encourage social interaction and keep the mind active.12345

Why are researchers excited about this trial?

Researchers are excited about the online gameplay intervention for mild cognitive impairment because it offers a novel approach to maintaining brain health. Unlike traditional treatments that may involve medications or cognitive therapies, this method leverages engaging online games to stimulate the brain. The intervention is designed to be accessible, with participants receiving brief educational sessions and ongoing support through technology, making it easy to integrate into daily life. This approach not only aims to enhance cognitive function but also promotes social interaction, which is an important factor in supporting mental health.

What evidence suggests that online gameplay is effective for reducing loneliness and isolation in adults with mild cognitive impairment?

Research shows that playing online games can benefit people with mild cognitive impairment (MCI). In this trial, participants in the Online Gameplay Intervention Group will engage in digital games. Studies have found that these games can boost thinking skills, improve mood, and enhance the quality of life for older adults with MCI or mild dementia. A review of multiple studies found that these digital activities can improve mental abilities in middle-aged and older adults. Additionally, serious games have increased social interaction and reduced loneliness. Overall, early findings suggest that playing these games can support brain health and encourage social connections.13567

Who Is on the Research Team?

KV

Kayci Vickers, PhD

Principal Investigator

Emory University

Are You a Good Fit for This Trial?

Adults aged 50-85 with mild cognitive impairment (MCI), fluent in English, living independently, and able to see/hear a computer screen can join. They must have a MoCA score of 18-25 and be capable of daily activities without assistance. Those with medical conditions preventing participation, recent substance abuse, stroke-related impairments, major psychiatric issues or on psychoactive meds cannot join.

Inclusion Criteria

MoCA-Blind (converted to MoCA score) > 17
Additional Criteria for MCI Group: Existing diagnosis by HC professional, MoCA-Blind (converted to MoCA score) of 18-25, FAQ < 9
Fluent in English
See 3 more

Exclusion Criteria

Medical illnesses that would prevent participation
History of substance abuse within last two years
I have cognitive issues due to a stroke or brain injury, not because of Alzheimer's or similar diseases.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Waitlist Control

Participants in the waitlist control group will wait for 12 weeks before beginning the gameplay intervention

12 weeks
Weekly calls

Gameplay Intervention

Participants engage in online gameplay 3 times per week for 12 weeks to support social engagement

12 weeks
Weekly calls

Follow-up

Participants are monitored for changes in social engagement, isolation, and loneliness

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Online Gameplay Intervention

Trial Overview

The study is testing if playing games online can help adults feel less lonely and more socially engaged. It includes those with MCI and compares active participants against a waitlist control group to measure the impact on social interaction and cognitive health.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Wait-list control GroupExperimental Treatment1 Intervention
Group II: Online Gameplay Intervention GroupExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Emory University

Lead Sponsor

Trials
1,735
Recruited
2,605,000+

National Institute on Aging (NIA)

Collaborator

Trials
1,841
Recruited
28,150,000+

Citations

Effectiveness of online‐based cognitive intervention in ...

ICT‐based cognitive intervention had a positive effect on cognitive function, depression, and quality of life in older adults with MCI or mild dementia.

GAMES Intervention in MCI (Mild Cognitive Impairment)

The objective of the present study is to evaluate whether online, remote gameplay can facilitate social engagement and reduce feelings of ...

Effectiveness of digital interventions in middle-aged and ...

Effectiveness of digital interventions in middle-aged and older adults with mild cognitive impairment: A systematic review and meta-analysis of randomized ...

Effects of Serious Games in Older Adults With Mild ...

This review summarizes randomized clinical trials (RCTs) exploring the impact of serious games on MCI patients.

Effects of virtual reality-based interventions on cognitive ...

The findings indicate that VR interventions can significantly improve global cognition, attention, and quality of life in individuals with MCI.

6.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/40738100/

Esports Interventions for Dementia and Mild Cognitive ...

Current evidence is insufficient to support esports as a therapeutic approach for dementia or MCI. Although participants consistently ...

Effects of Electronic Serious Games on Older Adults With ...

This meta-analysis examined the effectiveness of digital SGs in improving cognitive ability, enhancing daily behavioral capacity, and alleviating depression in ...