IgY Supplement for Immune System Support

GD
IW
Overseen ByIsaac Wong, MBT
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether a supplement called Muno-IgY (an IgY supplement) can boost the immune system over six weeks. Participants will take the supplement daily to assess its impact on overall immune health. The study seeks adults who can swallow a capsule and are not on regular prescription medications that might interfere with the trial. It is ideal for those without recent major health issues or dietary restrictions related to eggs. As a Phase 1 trial, the research focuses on understanding how the treatment works in people, offering participants the opportunity to be among the first to receive this new supplement.

Will I have to stop taking my current medications?

Yes, if you are using regular prescription medications like antihypertensives or antidepressants, you may not be eligible for the trial. Also, if you are taking proton pump inhibitors, you need a 48-hour break before taking the study capsules.

Is there any evidence suggesting that this treatment is likely to be safe for humans?

Previous studies have shown the IgY supplement to be safe. For instance, after 30 days of using IgY products, no serious liver problems occurred. Some individuals experienced minor side effects like diarrhea and gas, but these were not serious. When used correctly, IgY is considered possibly safe for adults for up to 26 weeks. In animal studies, IgY was well-tolerated even when taken twice a day for 28 days. These findings suggest that the IgY supplement is generally safe for use.12345

Why do researchers think this study treatment might be promising?

The IgY supplement is unique because it uses antibodies derived from egg yolks to support the immune system, offering a natural and potentially safer alternative to synthetic drugs or vaccines. Unlike traditional treatments that might rely on chemicals or biologics with broader effects, IgY specifically targets pathogens without disrupting the body's normal flora. Researchers are excited about this treatment due to its targeted action and potential to minimize side effects, making it a promising option for enhancing immunity.

What evidence suggests that the IgY supplement is effective for enhancing immune health?

Research has shown that oral IgY supplements can reduce symptoms of gut infections and decrease inflammation. Unlike antibiotics, IgY supports healthy gut bacteria, which is important for a strong immune system. Studies indicate that IgY, a natural protein, targets harmful substances in the body and may improve immune function. These findings suggest that daily IgY supplements, which participants in this trial will ingest, could boost immune health.12678

Are You a Good Fit for This Trial?

Adults aged 18-65 who can swallow a capsule and are willing to keep their diet and exercise the same during the study. They must not be on medications that affect the trial, planning pregnancy, have egg allergies or certain diets, substance abuse issues, serious health conditions, recent cancer treatments, antibiotic use, pregnant or breastfeeding.

Inclusion Criteria

I can swallow a large capsule.
Signed Informed Consent; willing and able to comply with study procedures
Willing to maintain their diet and physical activity levels during the study

Exclusion Criteria

Planning to become pregnant
Alcohol or drug abuse
Egg allergy
See 17 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive the Muno-IgY supplement daily and are monitored for safety and effectiveness

6 weeks
Daily ingestion, regular monitoring

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • IgY supplement
Trial Overview The trial is testing Muno-IgY supplement's effectiveness in boosting immune health over six weeks. Participants will take this supplement to see if it has positive effects on their gut microbiome and overall immunity.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: IgY SupplementExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Nimble Science Ltd.

Lead Sponsor

Trials
11
Recruited
570+

IGY Immune Technologies & Life Sciences Inc.

Collaborator

Trials
1
Recruited
20+

Published Research Related to This Trial

Many dietary supplements claiming to boost the immune system have misleading labels that do not meet FDA standards, raising concerns about their reliability.
Quality control for these supplements is generally inadequate, which could affect their safety and effectiveness for consumers.
Dietary Supplement Labels May Be Inaccurate and Misleading.Rosenberg, K.[2022]
Immunonutrition, which includes nutrients like glutamine, omega-3 fatty acids, and arginine, has been studied for its potential to influence immune responses, but individual supplements generally showed no significant clinical efficacy in randomized controlled trials.
Commercial immunonutrition formulas have demonstrated better outcomes compared to standard nutrition support in some trials, but design flaws in these studies make it unclear whether the benefits are due to the immunonutrients themselves or the overall nutrition regimen.
Immunonutrition: can you be what you eat?Koretz, RL.[2019]

Citations

Long-Term Oral Administration of Hyperimmune Egg ...Oral administration of IgY can alleviate clinical symptoms of intestinal infections and reduce the local inflammatory process by inhibiting ...
IgY Supplement for Immune System SupportWhat is the purpose of this trial? This study is to evaluate whether Muno-IgY is effective in enhancing immune health among adults over a six week period.
Assessing the Safety of an IGY Supplement on the Gut ...This study is to evaluate whether Muno-IgY is effective in enhancing immune health among adults over a six week period. Detailed Description. The goal of ...
IgYs: on her majesty's secret serviceUnlike antibiotics, oral IgY supplements support the microbiome that plays a vital role in maintaining overall health, including immune system function. IgY ...
A systematic review of the avian antibody (IgY) therapeutic ...Immunoglobulin Y, a natural protein that specifically targets foreign antigens, holds promise as a potential therapeutic option, particularly for individuals ...
HYPERIMMUNE EGG - Uses, Side Effects, and MoreWhen taken by mouth: Hyperimmune egg is POSSIBLY SAFE for adults when used appropriately for up to 26 weeks. Some people may experience diarrhea, gas, and ...
Egg-Derived Anti-SARS-CoV-2 Immunoglobulin Y (IgY ...Together, our data show that long-term twice-daily administration of 4 mg/mL IgY (or 16 mg/kg) up to 28 days in rats has excellent safety and tolerability with ...
8/13/21 IgY Max White PaperIgY antibodies have three to five times higher immunogenicity than IgG antibodies (17). Higher immunogenicity makes it feasible to produce ...
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