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Behavioral Intervention

Episodic Future Thinking for Cocaine Use Disorder

N/A
Recruiting
Led By Stephen LaConte, PhD
Research Sponsored by Virginia Polytechnic Institute and State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up over four weeks of participation
Awards & highlights

Study Summary

This trial explores how thinking about the future can help people with cocaine use disorder change their behavior.

Who is the study for?
This trial is for adults over 18 with Cocaine Use Disorder (CUD) who have used cocaine recently and want to reduce their use but aren't planning to enter treatment soon. It's not for those with MRI contraindications, psychotic disorders, severe opioid use disorder, or a history of seizures or brain injury.Check my eligibility
What is being tested?
The study tests how changing the way people think about the future affects their cocaine use. Participants will either engage in Episodic Future Thinking (EFT), imagining future events, or they'll be part of a control group focusing on general thoughts.See study design
What are the potential side effects?
Since this trial involves psychological interventions rather than medications, traditional side effects are not expected. However, participants may experience discomfort when discussing personal goals or reflecting on potential futures.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~over four-weeks of participation (weekly for four weeks)
This trial's timeline: 3 weeks for screening, Varies for treatment, and over four-weeks of participation (weekly for four weeks) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Cocaine Demand
Change in Delay Discounting
Cocaine Craving
+2 more
Secondary outcome measures
Cocaine Urinalysis
Daily Cocaine Use

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Episodic Future Thinking (EFT)Experimental Treatment1 Intervention
Participants will generate positive future events they are looking forward to at several time points in the future (e.g., 2 weeks, 1 month, 3 months, 1 year, and 5 years). Participants will be reminded of these events using cues throughout the study and instructed to think about these cues as they make their decisions. This intervention will be tested in both the presence and absence of stress probes.
Group II: Control Episodic Thinking (CET)Placebo Group1 Intervention
Participants will generate positive recent past events that have happened to them at several time points in the previous day (e.g., 7pm-10pm, 4pm-7pm, 1pm-4pm, 10am-1pm, and 7am-10am). Participants will be reminded of these events using cues throughout the study and instructed to think about these cues as they make their decisions. This intervention will be tested in both the presence and absence of stress probes.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Episodic Future Thinking (EFT)
2017
N/A
~100

Find a Location

Who is running the clinical trial?

Virginia Polytechnic Institute and State UniversityLead Sponsor
143 Previous Clinical Trials
27,713 Total Patients Enrolled
Carilion ClinicOTHER
72 Previous Clinical Trials
12,662 Total Patients Enrolled
Arizona State UniversityOTHER
283 Previous Clinical Trials
109,414 Total Patients Enrolled

Media Library

Episodic Future Thinking (EFT) (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05507814 — N/A
Cocaine Use Disorder Research Study Groups: Control Episodic Thinking (CET), Episodic Future Thinking (EFT)
Cocaine Use Disorder Clinical Trial 2023: Episodic Future Thinking (EFT) Highlights & Side Effects. Trial Name: NCT05507814 — N/A
Episodic Future Thinking (EFT) (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05507814 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this experiment currently admit participants?

"Affirmative. Clinicaltrials.gov's records show that the research project, initially published on November 30th 2022, is now actively recruiting individuals for participation. 100 volunteers are needed from a single trial site."

Answered by AI

What is the aggregate figure for enrollees in this research project?

"Affirmative. Clinicaltrials.gov indicates that this research project, which was first published on November 30th 2022, is presently actively recruiting participants. 100 patients are required to be enrolled from a single medical site."

Answered by AI
~39 spots leftby Mar 2025